Specific changes of enteric mycobiota and virome in inflammatory bowel disease

One of the important features of inflammatory bowel disease (IBD) is dysbiosis of the gut microbiota. It has been well documented that changes in the commensal bacterial population are involved in IBD development. However, the function of the fungal and viral communities in IBD remains unclear. More...

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Bibliographic Details
Published in:Journal of digestive diseases 2018-01, Vol.19 (1), p.2-7
Main Authors: Chu, Yi, Jiang, Ming Zuo, Xu, Bing, Wang, Wei Jie, Chen, Di, Li, Xiao Wei, Zhang, Yu Jie, Liang, Jie
Format: Article
Language:English
Subjects:
Dysbacteriosis
dysbiosis
Inflammatory bowel disease
Inflammatory bowel diseases
Intestinal microflora
Intestine
Microbiota
mycobiota
Therapeutic applications
virome
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Summary:One of the important features of inflammatory bowel disease (IBD) is dysbiosis of the gut microbiota. It has been well documented that changes in the commensal bacterial population are involved in IBD development. However, the function of the fungal and viral communities in IBD remains unclear. Moreover, the optimal treatment for IBD patients with opportunistic infections is still undecided. This review focused on how the enteric mycobiota and virome changes during the pathogenesis of IBD and discussed potential treatment strategies that open new insights into the managements of IBD.
ISSN:1751-2972
1751-2980
DOI:10.1111/1751-2980.12570