Reversal of Brugada electrocardiographic pattern with sodium bicarbonate solution after amitriptyline overdose

A Brugada electrocardiographic pattern (BEP) associated with tricyclic antidepressant (TCA) overdose has been reported rarely, but its reversal by sodium bicarbonate has not been described previously. We reported a case of amitriptyline overdose induced Type 1 BEP which was reversed by 150 mEq of in...

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Bibliographic Details
Published in:Clinical toxicology (Philadelphia, Pa.) Pa.), 2008-11, Vol.46 (9), p.892-896
Main Authors: Chan, Ho Yin, Chan, Yiu Cheung, Lau, Fei Lung
Format: Article
Language:English
Subjects:
Adult
Amitriptyline - poisoning
Antidepressive Agents, Tricyclic - poisoning
Biological and medical sciences
Brugada Syndrome - chemically induced
Drug intoxications. Doping
Drug Overdose - drug therapy
Electrocardiography
Humans
Male
Medical sciences
Pharmacology. Drug treatments
Sodium Bicarbonate - therapeutic use
Suicide
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Summary:A Brugada electrocardiographic pattern (BEP) associated with tricyclic antidepressant (TCA) overdose has been reported rarely, but its reversal by sodium bicarbonate has not been described previously. We reported a case of amitriptyline overdose induced Type 1 BEP which was reversed by 150 mEq of intravenous sodium bicarbonate.
ISSN:1556-3650
1556-9519
DOI:10.1080/15563650802293984