Chemical analysis and biological activities of the essential oil of Teucrium leucocladum Boiss. (Lamiaceae)

The chemical composition of the water-distilled essential oil and n-hexane–ether extract of Teucrium leucocladum Boiss. were determined by GLC and GLC–MS. Altogether 72 compounds were identified. The sesquiterpene alcohols, patchouli alcohol (31.24% and 29.66%) and α-cadinol (9.29% and 21.54%) were...

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Bibliographic Details
Published in:Biochemical systematics and ecology 2004-07, Vol.32 (7), p.665-674
Main Authors: El-Shazly, Assem M, Hussein, Karam T
Format: Article
Language:English
Subjects:
Antimicrobial
antimicrobial properties
Bacillus subtilis
Candida albicans
Ceratitis capitata
chemical constituents of plants
Culex pipiens
Essential oil
essential oils
Lamiaceae
larvicicidal properties
Larvicidal
Musca domestica
n-Hexane–ether extract
Patchouli alcohol
Pseudomonas aeruginosa
Teucrium
Teucrium leucocladum
α-Cadinol
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Summary:The chemical composition of the water-distilled essential oil and n-hexane–ether extract of Teucrium leucocladum Boiss. were determined by GLC and GLC–MS. Altogether 72 compounds were identified. The sesquiterpene alcohols, patchouli alcohol (31.24% and 29.66%) and α-cadinol (9.29% and 21.54%) were the main components in the oil and the extract, respectively. α-Cadinol was isolated and characterized using MS, 1H- and 13C-NMR spectral analyses. Furthermore, the oil and the extract were tested for their bacterostatic and antifungal activities; they showed broad and potent activity against Pseudomonas aeruginosa, Bacillus subtilis and Candida albicans. A marked larvicidal activity of the essential oil, n-hexane–ether extract and crude ethanolic extract was also observed against Culex pipiens, Musca domestica and Ceratitis capitata larvae.
ISSN:0305-1978
1873-2925
DOI:10.1016/j.bse.2003.12.009