Nanocarrier‐Mediated Photochemotherapy and Photoradiotherapy

Photothermal therapy (PTT) and photodynamic therapy (PDT) both utilize light to induce a therapeutic effect. These therapies are rapidly gaining importance due to the noninvasiveness of light and the limited adverse effect associated with these treatments. However, most preclinical studies show that...

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Bibliographic Details
Published in:Advanced healthcare materials 2018-04, Vol.7 (8), p.e1701211-n/a
Main Authors: Denkova, Antonia G., de Kruijff, Robine M., Serra‐Crespo, Pablo
Format: Article
Language:English
Subjects:
Chemotherapy
combined phototherapies
Combined treatment
nanocarriers
Photochemotherapy
Photodynamic therapy
Radiation therapy
Side effects
Tumors
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Summary:Photothermal therapy (PTT) and photodynamic therapy (PDT) both utilize light to induce a therapeutic effect. These therapies are rapidly gaining importance due to the noninvasiveness of light and the limited adverse effect associated with these treatments. However, most preclinical studies show that complete elimination of tumors is rarely observed. Combining PDT and PTT with chemotherapy or radiotherapy can improve the therapeutic outcome and simultaneously decrease side effects of these conventional treatments. Nanocarriers can help to facilitate such a combined treatment. Here, the most recent advancements in the field of photochemotherapy and photoradiotherapy, in which nanocarriers are employed, are reviewed. Photothermal therapy and photodynamic therapy both utilize light to induce a therapeutic effect. These therapies will benefit tremendously if combined with other therapies such as chemotherapy and radiotherapy. Nanocarriers can help to facilitate such a combined treatment. In this paper, the most recent advancements in the field of photochemotherapy and photoradiotherapy in which nanocarriers are employed are reviewed.
ISSN:2192-2640
2192-2659
DOI:10.1002/adhm.201701211