Randomized controlled clinical trial on the antiseptic efficacy of polihexanide 0.04% on acute traumatic wounds

Prevention of wound infections is a challenge in clinical practice. The aim of this study was to assess the efficacy of polyhexamethylene biguanide (PHMB, polihexanide) 0.04% on acute traumatic wounds. It was a randomized, double-blind, placebo-controlled prospective trial which included 61 patients...

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Bibliographic Details
Published in:The Journal of hospital infection 2018-04, Vol.98 (4), p.429-432
Main Authors: Payne, B., Simmen, H.-P., Csuka, E., Hintzpeter, M., Pahl, S., Brill, F.H.H.
Format: Article
Language:English
Subjects:
Antiseptic
Efficacy
Polihexanide
Polyhexamethylene biguanide
Traumatic wounds
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Summary:Prevention of wound infections is a challenge in clinical practice. The aim of this study was to assess the efficacy of polyhexamethylene biguanide (PHMB, polihexanide) 0.04% on acute traumatic wounds. It was a randomized, double-blind, placebo-controlled prospective trial which included 61 patients. The polihexanide group showed a significant decrease in log10 colony-forming units (cfu) (P 
ISSN:0195-6701
1532-2939
DOI:10.1016/j.jhin.2017.12.020