Cognitive, physical, and mental health outcomes between long-term cannabis and tobacco users

• Published in: Addictive behaviors 2018-04, Vol.79, p.178-188
• Main Authors: Lovell, M.E., Bruno, R., Johnston, J., Matthews, A., McGregor, I., Allsop, D.J., Lintzeris, N.
• Format: Article
• Language: English
• Subjects: Adult; Adults; Cannabis; Cognition; Cognition & reasoning; Cognitive ability; Cognitive tasks; Drug abuse; Drug addiction; Drug use; Executive function; Information processing; Inhibition; Intoxication; Learning; Marijuana; Memory; Mental disorders; Mental health; Tobacco; User satisfaction
• ISSN: 0306-4603; 1873-6327
• DOI: 10.1016/j.addbeh.2017.12.009

Cannabis intoxication adversely affects health, yet persistent effects following short-term abstinence in long-term cannabis users are unclear. This matched-subjects, cross-sectional study compared health outcomes of long-term cannabis and long-term tobacco-only users, relative to population norms. Nineteen long-term (mean 32.3years of use, mean age 55.7years), abstinent (mean 15h) cannabis users and 16 long-term tobacco users (mean 37.1years of use, mean age 52.9years), matched for age, educational attainment, and lifetime tobacco consumption, were compared on measures of learning and memory, response inhibition, information-processing, sustained attention, executive control, and mental and physical health. Cannabis users exhibited poorer overall learning and delayed recall and greater interference and forgetting than tobacco users, and exhibited poorer recall than norms. Inhibition and executive control were similar between groups, but cannabis users had slower reaction times during information processing and sustained attention tasks. Cannabis users had superior health satisfaction and psychological, somatic, and general health than tobacco users and had similar mental and physical health to norms whilst tobacco users had greater stress, role limitations from emotional problems, and poorer health satisfaction. Long-term cannabis users may exhibit deficits in some cognitive domains despite short-term abstinence and may therefore benefit from interventions to improve cognitive performance. Tobacco alone may contribute to adverse mental and physical health outcomes, which requires appropriate control in future studies. •We examined health outcomes of long-term cannabis users and long-term tobacco users.•Cannabis users had poorer learning and memory than tobacco users.•Cannabis users had slower reaction time on some tasks than tobacco users.•Tobacco users reported poorer physical and mental health than cannabis users.•Tobacco should be controlled in research investigating cannabis health outcomes.