Screening study for potential lead compounds for natural product-based fungicides. I. Synthesis and in vitro evaluation of coumarins against Botrytis cinerea

An efficient, one-pot synthesis of angular and linear dihydropyranocoumarins, along with C-6 and C-8 prenylated coumarins is reported. These compounds, together with single- and furanocoumarins, were tested for their potential antifungal activity against the phytopathogen Botrytis cinerea Pers ex Fr...

Full description

Saved in:
Bibliographic Details
Published in:Pest management science 2004-09, Vol.60 (9), p.927-932
Main Authors: Daoubi, M, Duran-Patron, R, Hmamouchi, M, Hernandez-Galan, R, Benharref, A, Collado, I.G
Format: Article
Language:English
Subjects:
antifungal activity
antifungal properties
Atoms & subatomic particles
biochemical pathways
Biological and medical sciences
Biological Factors - chemical synthesis
Biological Factors - toxicity
Botrytis - drug effects
Botrytis cinerea
chemical reactions
chemical structure
Control
coumarins
Coumarins - chemical synthesis
Coumarins - toxicity
crop-protection agents
Culture Techniques
disease control
Fundamental and applied biological sciences. Psychology
fungal diseases of plants
Fungal plant pathogens
Fungi
Fungicides, Industrial - chemical synthesis
Fungicides, Industrial - toxicity
Furocoumarins - chemical synthesis
Furocoumarins - toxicity
lead
Lead content
natural fungicides
Natural products
Pest Control, Biological - methods
Pesticides
Phytopathology. Animal pests. Plant and forest protection
plant pathogenic fungi
Protein Prenylation
synthesis
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:An efficient, one-pot synthesis of angular and linear dihydropyranocoumarins, along with C-6 and C-8 prenylated coumarins is reported. These compounds, together with single- and furanocoumarins, were tested for their potential antifungal activity against the phytopathogen Botrytis cinerea Pers ex Fr. The results show that furanocoumarins may be able to control the fungus B cinerea.
ISSN:1526-498X
1526-4998
DOI:10.1002/ps.891