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Antibacterial Activity of Marine Bacterium Pseudomonas sp. Associated with Soft Coral Sinularia polydactyla against Streptococcus equi Subsp. zooepidemicus

A marine bacterium associated with soft coral Sinularia polydactyla collected from Bandengan water, Jepara, North Java Sea, Indonesia, was successfully screened for antibacterial activity against pathogenic bacterium Streptococcus equi subsp. zooepidemicus K6.72 isolated from infected monkey of the...

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Published in:International journal of pharmacology 2007-04, Vol.3 (2), p.170-174
Main Authors: Radjasa, Ocky Karna, Salasia, Siti Isrina Oktavia, Sabdono, Agus, Weise, Jutta, Imhoff, Johannes F., Lammler, Christop, Risk, Michael J.
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container_title International journal of pharmacology
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creator Radjasa, Ocky Karna
Salasia, Siti Isrina Oktavia
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description A marine bacterium associated with soft coral Sinularia polydactyla collected from Bandengan water, Jepara, North Java Sea, Indonesia, was successfully screened for antibacterial activity against pathogenic bacterium Streptococcus equi subsp. zooepidemicus K6.72 isolated from infected monkey of the island of Bali and identified based on morphological, biochemical and molecular methods. Marine bacterium was identified as Pseudomonas sp. based on its 16S rDNA and was found to amplify gene fragments of Non-ribosomal peptide synthetase (NRPS). Cloning and subsequent sequencing, a 360 bp long DNA fragment was obtained and the deduced amino acid sequence showed conserved signature regions for peptide synthetases and revealed a high similarity of 61.1% to genes peptide synthetase of Bacillus subtilis.
doi_str_mv 10.3923/ijp.2007.170.174
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source Full-Text Journals in Chemistry (Open access)
subjects Bacillus subtilis
Pseudomonas
Sinularia polydactyla
Streptococcus equi
title Antibacterial Activity of Marine Bacterium Pseudomonas sp. Associated with Soft Coral Sinularia polydactyla against Streptococcus equi Subsp. zooepidemicus
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