Prenatal sonographic monitoring of progressive cardiac damages caused by anti-Ro antibodies: A case report

Maternal autoantibodies to Ro/SSA are often linked to congenital heart block and rarely associated with structural defects. We describe the case of a fetus with anti-Ro-mediated second-degree block at 19 weeks, which progressed to a complete block, fibroelastosis, atrioventricular valve insufficienc...

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Bibliographic Details
Published in:Journal of clinical ultrasound : JCU 2018, Vol.46 (5), p.347-350
Main Authors: Tongprasert, Fuanglada, Sittiwangkul, Rekwan, Lerthiranwong, Thitikarn, Tongsong, Theera
Format: Report
Language:English
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Summary:Maternal autoantibodies to Ro/SSA are often linked to congenital heart block and rarely associated with structural defects. We describe the case of a fetus with anti-Ro-mediated second-degree block at 19 weeks, which progressed to a complete block, fibroelastosis, atrioventricular valve insufficiency, and semilunar valve stenosis/insufficiency at 20, 22, 24, and 26 weeks, respectively, although the fetus received transplacental anti-arrhythmic drugs. The 2150-g fetus was vaginally delivered at 35 weeks. An external pacemaker was inserted immediately after birth and replaced with permanent pacemaker at the age of 3 months. The newborn has had a good outcome with well-controlled heart rate.
ISSN:1097-0096
DOI:10.1002/jcu.22541