Iridoids from Gardenia jasminoides

The dichloromethane extract of the air-dried flowers of Gardenia jasminoides Ellis. afforded a new iridoid natural product (1), and a diastereomeric mixture of two new iridoids (2a and 2b) in a 2 : 1 ratio. Their structures were elucidated by extensive 1D and 2D NMR spectroscopy. Antimicrobial tests...

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Bibliographic Details
Published in:Natural product research 2007-10, Vol.21 (12), p.1078-1084
Main Authors: Ragasa, Consolacion Y., Pimenta, Leslie Elline N., Rideout, John A.
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - chemistry
Anti-Bacterial Agents - pharmacology
Antifungal Agents - chemistry
Antifungal Agents - pharmacology
Aspergillus niger
Bacillus subtilis
Bacteria - drug effects
Candida albicans
Candida albicans - drug effects
Escherichia coli
Flowers - chemistry
Gardenia - chemistry
Gardenia jasminoides
Gardenia jasminoides Ellis
Iridoids
Iridoids - chemistry
Magnetic Resonance Spectroscopy
Molecular Structure
Pseudomonas aeruginosa
Rubiaceae
Staphylococcus aureus
Trichophyton mentagrophytes
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Summary:The dichloromethane extract of the air-dried flowers of Gardenia jasminoides Ellis. afforded a new iridoid natural product (1), and a diastereomeric mixture of two new iridoids (2a and 2b) in a 2 : 1 ratio. Their structures were elucidated by extensive 1D and 2D NMR spectroscopy. Antimicrobial tests on 1 indicated that it was moderately active against Candida albicans; slightly active against E. coli, Pseudomonas aeruginosa, Staphylococcus. aureus, and Trichophyton mentagrophytes; and inactive against Bacillus subtilis and Aspergillus niger.
ISSN:1478-6419
1478-6427
DOI:10.1080/14786410701589998