Forensic parameters of the X-STR Decaplex system in Mexican populations

•Mexican populations from five geographic regions were studied.•Allele frequencies and forensic parameters of the X-STR Decaplex system are reported.•A relative genetic homogeneity was observed among Mexican populations from different regions.A global Mexican database could be used for forensic inte...

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Bibliographic Details
Published in:Legal medicine (Tokyo, Japan) Japan), 2018-03, Vol.31, p.38-41
Main Authors: Mariscal Ramos, C., Martínez-Cortes, G, Ramos-González, B, Rangel-Villalobos, H
Format: Article
Language:English
Subjects:
Decaplex
Human identification
Mexican population
X-STRs
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Summary:•Mexican populations from five geographic regions were studied.•Allele frequencies and forensic parameters of the X-STR Decaplex system are reported.•A relative genetic homogeneity was observed among Mexican populations from different regions.A global Mexican database could be used for forensic interpretation of X-STR Decaplex genotypes. We studied the X-STR decaplex system in 529 DNA female samples of Mexican populations from five geographic regions. Allele frequencies and forensic parameters were estimated in each region and in the pooled Mexican population. Genotype distribution by locus was in agreement with Hardy-Weinberg expectations in each Mexican population sample. Similarly, linkage equilibrium was demonstrated between pair of loci. Pairwise comparisons and genetic distances between Mexican, Iberoamerican and one African populations were estimated and graphically represented. Interestingly, a non-significant interpopulation differentiation was detected (Fst = 0.0021; p = .74389), which allows using a global Mexican database for forensic interpretation of X-STR genotypes.
ISSN:1344-6223
1873-4162
DOI:10.1016/j.legalmed.2017.12.013