Synthesis of functionalized dihydro-2-oxopyrroles using graphene oxide as heterogeneous catalyst

A mild, efficient synthetic approach for the synthesis of highly functionalized dihydro-2-oxopyrroles is developed by using graphene oxide, a readily available and inexpensive material, as an eco-benign solid acid catalyst in ethanol at room temperature. The present methodology displays several adva...

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Bibliographic Details
Published in:Molecular diversity 2018-08, Vol.22 (3), p.561-573
Main Authors: Bavadi, Masoumeh, Niknam, Khodabakhsh
Format: Article
Language:English
Subjects:
Biochemistry
Biomedical and Life Sciences
Ethanol
Life Sciences
Organic Chemistry
Original Article
Pharmacy
Polymer Sciences
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Summary:A mild, efficient synthetic approach for the synthesis of highly functionalized dihydro-2-oxopyrroles is developed by using graphene oxide, a readily available and inexpensive material, as an eco-benign solid acid catalyst in ethanol at room temperature. The present methodology displays several advantages such as practical simplicity, high atom economy, easy workup procedure, and high yields of the products. Graphical Abstract
ISSN:1381-1991
1573-501X
DOI:10.1007/s11030-017-9809-9