Effectiveness and safety of foam sclerotherapy with 5% ethanolamine oleate in the treatment of low-flow venous malformations in the head and neck region: a case series

• Published in: International journal of oral and maxillofacial surgery 2018-07, Vol.47 (7), p.900-907
• Main Authors: Ribeiro, M.C., de Mattos Camargo Grossmann, S., do Amaral, M.B.F., de Castro, W.H., Navarro, T.P., Procopio, R.J., da Silva, T.A., de Nazaré Alves de Oliveira Kato, C., Mesquita, R.A.
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Aged; Arteriovenous Malformations - therapy; Child; Dentistry; Female; foam sclerotherapy; Head - blood supply; Humans; Male; Middle Aged; Neck - blood supply; Oleic Acids - therapeutic use; Sclerosing Solutions - therapeutic use; Sclerotherapy - methods; treatment; Treatment Outcome; vascular anomalies; vascular malformation
• ISSN: 0901-5027; 1399-0020
• DOI: 10.1016/j.ijom.2017.12.004

The aim of this study was to evaluate the effectiveness and safety of 5% ethanolamine oleate (EO) foam in the treatment of low-flow venous malformations in the head and neck region. Seventeen consecutive patients (six male, 11 female) and 34 low-flow venous malformations were enrolled. The vascular anomalies ranged between 20mm and 80mm in size. The typical clinical indication was a swelling (88.2%) with a purple colour (85.3%); the most frequent location was the tongue (23.5%). Ethanolamine oleate foam was produced via the Tessari method and applied at 10mg per 1cm to the vascular anomalies. This process resulted in the highest clinical healing score in 64.7% of cases, and half of the patients reported a high level of satisfaction (score >9). In the majority of cases (88.2%), the patients reported that the pain immediately postoperative was mild or moderate. There were direct relationships between vascular anomaly size and the volume of EO applied, the number of sessions, and healing (P