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Bartonella henselae: Serological evidence in pediatric patients with clinical suspicion of cat scratch disease

Cat scratch disease (CSD) is caused by Bartonella henselae, which mainly affects children. The cat is the reservoir. The laboratory diagnosis is based on the detection of antibodies by the Indirect Immunofluorescence (IFI) assay. The objective of this study was to analyze the serological evidence of...

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Published in:Revista argentina de microbiología 2018-10, Vol.50 (4), p.365-368
Main Authors: Armitano, Rita, Lisa, Agustina, Martínez, Claudia, Cipolla, Lucia, Iachini, Ricardo, Prieto, Monica
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container_title Revista argentina de microbiología
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creator Armitano, Rita
Lisa, Agustina
Martínez, Claudia
Cipolla, Lucia
Iachini, Ricardo
Prieto, Monica
description Cat scratch disease (CSD) is caused by Bartonella henselae, which mainly affects children. The cat is the reservoir. The laboratory diagnosis is based on the detection of antibodies by the Indirect Immunofluorescence (IFI) assay. The objective of this study was to analyze the serological evidence of B. henselae infection in pediatric patients that met the clinical/epidemiological criteria for suspected CSD. We studied 92 patients, who were categorized into four serological groups: 1) IgG (+)/IgM(+), 31,5% (n=29); 2) IgG (-)/IgM(+), 10,9% (n=10); 3) IgG (+)/IgM(-), 9,8% (n=9); 4) IgG (-)/IgM(-), 47,8% (n=44). These findings aim to promote future works for investigating the seroprevalence of Bartonella spp. in Argentina, which will allow us to know the importance of this zoonosis in our population and to evaluate new cut-off points of the technique.
doi_str_mv 10.1016/j.ram.2017.10.004
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title Bartonella henselae: Serological evidence in pediatric patients with clinical suspicion of cat scratch disease
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