CKD-EPI versus Cockcroft-Gault formula for predicting contrast-induced nephropathy following percutaneous coronary intervention in patients without significant renal impairment

• Published in: Revista portuguesa de cardiologia 2018-01, Vol.37 (1), p.25-33
• Main Authors: Nunes, Mário B G, Filho, Antônio C, Alvares, Valéria R C, Meneguz-Moreno, Rafael, Lamas, Edgar, Loures, Vitor, Chamié, Daniel, Abizaid, Alexandre
• Format: Article
• Language: eng ; por
• ISSN: 2174-2030; 2174-2049
• DOI: 10.1016/j.repc.2017.05.009

Individuals with glomerular filtration rate (GFR) ≥60 ml/min/1.73 m estimated by the Cockcroft-Gault formula (CG) who undergo percutaneous coronary intervention (PCI) frequently develop contrast-induced nephropathy (CIN). This study aimed to assess whether individuals with significant renal impairment assessed by the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula, but not by CG, more often develop CIN following PCI than those without renal impairment by either formula. In this cross-sectional study analyzing patients with baseline CG GFR ≥60 ml/min/1.73 m before PCI, subjects were divided into two groups according to CIN occurrence. Baseline CKD-EPI GFR was calculated for all patients. We analyzed 140 patients. Baseline GFR was 87.5±21.3 and 77.1±15.0 ml/min/1.73 m for CG and CKD-EPI, respectively. CIN occurred in 84.6% of individuals with baseline CKD-EPI GFR