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Robot-assisted post-chemotherapy retroperitoneal lymph node dissection in germ cell tumor: is the single-docking with lateral approach relevant?
Introduction Surgical treatment of post-chemotherapy residual mass of germ cell tumor (GCT) may be performed in various techniques. We assess the feasibility, safety, and efficacy of single-docking with lateral approach robot-assisted retroperitoneal lymph node dissection (R-RPLND) in residual mass...
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| Published in: | World journal of urology 2018-04, Vol.36 (4), p.655-661 |
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| container_title | World journal of urology |
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| creator | Overs, C. Beauval, J. B. Mourey, L. Rischmann, P. Soulié, M. Roumiguié, M. Doumerc, Nicolas |
| description | Introduction
Surgical treatment of post-chemotherapy residual mass of germ cell tumor (GCT) may be performed in various techniques. We assess the feasibility, safety, and efficacy of single-docking with lateral approach robot-assisted retroperitoneal lymph node dissection (R-RPLND) in residual mass of GCT in our center.
Materials and methods
A retrospective review of patients undergoing R-RPLND for residual mass of CGT was performed between January 2014 and April 2017. Patients with residual mass |
| doi_str_mv | 10.1007/s00345-018-2177-y |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1989911872</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1993243691</sourcerecordid><originalsourceid>FETCH-LOGICAL-c372t-49cb9771db8edb250512d5a84b1d28b4ac03c9c8f0bc5a990fdbcab260be75503</originalsourceid><addsrcrecordid>eNp1kc2KFTEQhYMozp3RB3AjATduovnpvum4ERl0FAYE0XWTn7rTGdNJm6SVfgsf2VzuKCK4qkB9deqkDkJPGH3BKJUvC6Wi6wllA-FMSrLdQzvWCUEGyff30Y5K3pFODeIMnZdySymTe9o_RGdciV4I1u3Qz0_JpEp0Kb5UcHhJpRI7wZzqBFkvG85Qc1og-5oi6IDDNi8TjskBdr4UsNWniH3EN5BnbCEEXNc55VfYF9xEcPHxJgBxyX5tL_zD1wkHXZt6wHpZctJ2alsCfNexvn6EHhx0KPD4rl6gL-_efr58T64_Xn24fHNNrJC8tl9Zo6RkzgzgDO9pz7jr9dAZ5vhgOm2psMoOB2psr5WiB2esNnxPDci-p-ICPT_pNgPfVih1nH05utcR0lpGpgalGGuXbOizf9DbtObY3DVKCd6JvWKNYifK5lRKhsO4ZD_rvI2Mjse4xlNcY4trPMY1bm3m6Z3yamZwfyZ-59MAfgJKa8V24b9W_1f1FwNkpCE</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1993243691</pqid></control><display><type>article</type><title>Robot-assisted post-chemotherapy retroperitoneal lymph node dissection in germ cell tumor: is the single-docking with lateral approach relevant?</title><source>Springer Nature</source><creator>Overs, C. ; Beauval, J. B. ; Mourey, L. ; Rischmann, P. ; Soulié, M. ; Roumiguié, M. ; Doumerc, Nicolas</creator><creatorcontrib>Overs, C. ; Beauval, J. B. ; Mourey, L. ; Rischmann, P. ; Soulié, M. ; Roumiguié, M. ; Doumerc, Nicolas</creatorcontrib><description>Introduction
Surgical treatment of post-chemotherapy residual mass of germ cell tumor (GCT) may be performed in various techniques. We assess the feasibility, safety, and efficacy of single-docking with lateral approach robot-assisted retroperitoneal lymph node dissection (R-RPLND) in residual mass of GCT in our center.
Materials and methods
A retrospective review of patients undergoing R-RPLND for residual mass of CGT was performed between January 2014 and April 2017. Patients with residual mass < 3 cm for seminoma or < 1 cm for non-seminoma were eligible. All surgeries were performed with single-docking RPNLD technique in lateral decubitus. We assessed preoperative characteristics (age, testicular pathology, template, chemotherapy regimen, lesion size, and clinical stage), peroperative (operative time, estimated blood loss, intraoperative complication, node count, pathology, and number of positive node), and postoperative outcomes (postoperative complications, hospital length of stay, recurrence-free survival at 2 year, and ejaculation dysfunction).
Results
Eleven patients underwent R-RPLND with a median size of the residual mass of 20 mm. Median operative time was 153 min with 120 ml of estimated blood loss, without intraoperative complication. Median nodes count was 7 [1; 24]. Two patients had post-chemotherapy necrotic nodes and one no tumorous node. One patient had postoperative Clavien I complication (chyloperitoneum). We report 72.7% of antegrade ejaculation at 1 month from the surgery. Median clinical recurrence-free survival was 100% after 2 years from the surgery (
n
= 6).
Conclusion
Lateral approach with single-docking R-RPLND for residual mass of GCT is feasible and safe, with satisfying functional and oncologic outcomes.</description><identifier>ISSN: 0724-4983</identifier><identifier>EISSN: 1433-8726</identifier><identifier>DOI: 10.1007/s00345-018-2177-y</identifier><identifier>PMID: 29353314</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adult ; Biopsy ; Chemotherapy ; Disease-Free Survival ; Ejaculation ; Feasibility Studies ; France ; Humans ; Lymph ; Lymph Node Excision - adverse effects ; Lymph Node Excision - methods ; Lymph nodes ; Lymph Nodes - diagnostic imaging ; Lymph Nodes - pathology ; Lymph Nodes - surgery ; Lymphatic Metastasis ; Lymphatic system ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Neoplasm Staging ; Neoplasms, Germ Cell and Embryonal - pathology ; Neoplasms, Germ Cell and Embryonal - radiotherapy ; Nephrology ; Oncology ; Original Article ; Outcome and Process Assessment (Health Care) ; Postoperative Complications - diagnosis ; Postoperative Complications - epidemiology ; Retroperitoneal Space ; Robotic surgery ; Robotic Surgical Procedures - adverse effects ; Robotic Surgical Procedures - methods ; Seminoma ; Seminoma - pathology ; Seminoma - radiotherapy ; Testicular cancer ; Testicular Neoplasms - pathology ; Testicular Neoplasms - radiotherapy ; Urology</subject><ispartof>World journal of urology, 2018-04, Vol.36 (4), p.655-661</ispartof><rights>Springer-Verlag GmbH Germany, part of Springer Nature 2018</rights><rights>World Journal of Urology is a copyright of Springer, (2018). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-49cb9771db8edb250512d5a84b1d28b4ac03c9c8f0bc5a990fdbcab260be75503</citedby><cites>FETCH-LOGICAL-c372t-49cb9771db8edb250512d5a84b1d28b4ac03c9c8f0bc5a990fdbcab260be75503</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29353314$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Overs, C.</creatorcontrib><creatorcontrib>Beauval, J. B.</creatorcontrib><creatorcontrib>Mourey, L.</creatorcontrib><creatorcontrib>Rischmann, P.</creatorcontrib><creatorcontrib>Soulié, M.</creatorcontrib><creatorcontrib>Roumiguié, M.</creatorcontrib><creatorcontrib>Doumerc, Nicolas</creatorcontrib><title>Robot-assisted post-chemotherapy retroperitoneal lymph node dissection in germ cell tumor: is the single-docking with lateral approach relevant?</title><title>World journal of urology</title><addtitle>World J Urol</addtitle><addtitle>World J Urol</addtitle><description>Introduction
Surgical treatment of post-chemotherapy residual mass of germ cell tumor (GCT) may be performed in various techniques. We assess the feasibility, safety, and efficacy of single-docking with lateral approach robot-assisted retroperitoneal lymph node dissection (R-RPLND) in residual mass of GCT in our center.
Materials and methods
A retrospective review of patients undergoing R-RPLND for residual mass of CGT was performed between January 2014 and April 2017. Patients with residual mass < 3 cm for seminoma or < 1 cm for non-seminoma were eligible. All surgeries were performed with single-docking RPNLD technique in lateral decubitus. We assessed preoperative characteristics (age, testicular pathology, template, chemotherapy regimen, lesion size, and clinical stage), peroperative (operative time, estimated blood loss, intraoperative complication, node count, pathology, and number of positive node), and postoperative outcomes (postoperative complications, hospital length of stay, recurrence-free survival at 2 year, and ejaculation dysfunction).
Results
Eleven patients underwent R-RPLND with a median size of the residual mass of 20 mm. Median operative time was 153 min with 120 ml of estimated blood loss, without intraoperative complication. Median nodes count was 7 [1; 24]. Two patients had post-chemotherapy necrotic nodes and one no tumorous node. One patient had postoperative Clavien I complication (chyloperitoneum). We report 72.7% of antegrade ejaculation at 1 month from the surgery. Median clinical recurrence-free survival was 100% after 2 years from the surgery (
n
= 6).
Conclusion
Lateral approach with single-docking R-RPLND for residual mass of GCT is feasible and safe, with satisfying functional and oncologic outcomes.</description><subject>Adult</subject><subject>Biopsy</subject><subject>Chemotherapy</subject><subject>Disease-Free Survival</subject><subject>Ejaculation</subject><subject>Feasibility Studies</subject><subject>France</subject><subject>Humans</subject><subject>Lymph</subject><subject>Lymph Node Excision - adverse effects</subject><subject>Lymph Node Excision - methods</subject><subject>Lymph nodes</subject><subject>Lymph Nodes - diagnostic imaging</subject><subject>Lymph Nodes - pathology</subject><subject>Lymph Nodes - surgery</subject><subject>Lymphatic Metastasis</subject><subject>Lymphatic system</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Neoplasm Staging</subject><subject>Neoplasms, Germ Cell and Embryonal - pathology</subject><subject>Neoplasms, Germ Cell and Embryonal - radiotherapy</subject><subject>Nephrology</subject><subject>Oncology</subject><subject>Original Article</subject><subject>Outcome and Process Assessment (Health Care)</subject><subject>Postoperative Complications - diagnosis</subject><subject>Postoperative Complications - epidemiology</subject><subject>Retroperitoneal Space</subject><subject>Robotic surgery</subject><subject>Robotic Surgical Procedures - adverse effects</subject><subject>Robotic Surgical Procedures - methods</subject><subject>Seminoma</subject><subject>Seminoma - pathology</subject><subject>Seminoma - radiotherapy</subject><subject>Testicular cancer</subject><subject>Testicular Neoplasms - pathology</subject><subject>Testicular Neoplasms - radiotherapy</subject><subject>Urology</subject><issn>0724-4983</issn><issn>1433-8726</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNp1kc2KFTEQhYMozp3RB3AjATduovnpvum4ERl0FAYE0XWTn7rTGdNJm6SVfgsf2VzuKCK4qkB9deqkDkJPGH3BKJUvC6Wi6wllA-FMSrLdQzvWCUEGyff30Y5K3pFODeIMnZdySymTe9o_RGdciV4I1u3Qz0_JpEp0Kb5UcHhJpRI7wZzqBFkvG85Qc1og-5oi6IDDNi8TjskBdr4UsNWniH3EN5BnbCEEXNc55VfYF9xEcPHxJgBxyX5tL_zD1wkHXZt6wHpZctJ2alsCfNexvn6EHhx0KPD4rl6gL-_efr58T64_Xn24fHNNrJC8tl9Zo6RkzgzgDO9pz7jr9dAZ5vhgOm2psMoOB2psr5WiB2esNnxPDci-p-ICPT_pNgPfVih1nH05utcR0lpGpgalGGuXbOizf9DbtObY3DVKCd6JvWKNYifK5lRKhsO4ZD_rvI2Mjse4xlNcY4trPMY1bm3m6Z3yamZwfyZ-59MAfgJKa8V24b9W_1f1FwNkpCE</recordid><startdate>20180401</startdate><enddate>20180401</enddate><creator>Overs, C.</creator><creator>Beauval, J. B.</creator><creator>Mourey, L.</creator><creator>Rischmann, P.</creator><creator>Soulié, M.</creator><creator>Roumiguié, M.</creator><creator>Doumerc, Nicolas</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7T5</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20180401</creationdate><title>Robot-assisted post-chemotherapy retroperitoneal lymph node dissection in germ cell tumor: is the single-docking with lateral approach relevant?</title><author>Overs, C. ; Beauval, J. B. ; Mourey, L. ; Rischmann, P. ; Soulié, M. ; Roumiguié, M. ; Doumerc, Nicolas</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-49cb9771db8edb250512d5a84b1d28b4ac03c9c8f0bc5a990fdbcab260be75503</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adult</topic><topic>Biopsy</topic><topic>Chemotherapy</topic><topic>Disease-Free Survival</topic><topic>Ejaculation</topic><topic>Feasibility Studies</topic><topic>France</topic><topic>Humans</topic><topic>Lymph</topic><topic>Lymph Node Excision - adverse effects</topic><topic>Lymph Node Excision - methods</topic><topic>Lymph nodes</topic><topic>Lymph Nodes - diagnostic imaging</topic><topic>Lymph Nodes - pathology</topic><topic>Lymph Nodes - surgery</topic><topic>Lymphatic Metastasis</topic><topic>Lymphatic system</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Neoplasm Staging</topic><topic>Neoplasms, Germ Cell and Embryonal - pathology</topic><topic>Neoplasms, Germ Cell and Embryonal - radiotherapy</topic><topic>Nephrology</topic><topic>Oncology</topic><topic>Original Article</topic><topic>Outcome and Process Assessment (Health Care)</topic><topic>Postoperative Complications - diagnosis</topic><topic>Postoperative Complications - epidemiology</topic><topic>Retroperitoneal Space</topic><topic>Robotic surgery</topic><topic>Robotic Surgical Procedures - adverse effects</topic><topic>Robotic Surgical Procedures - methods</topic><topic>Seminoma</topic><topic>Seminoma - pathology</topic><topic>Seminoma - radiotherapy</topic><topic>Testicular cancer</topic><topic>Testicular Neoplasms - pathology</topic><topic>Testicular Neoplasms - radiotherapy</topic><topic>Urology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Overs, C.</creatorcontrib><creatorcontrib>Beauval, J. B.</creatorcontrib><creatorcontrib>Mourey, L.</creatorcontrib><creatorcontrib>Rischmann, P.</creatorcontrib><creatorcontrib>Soulié, M.</creatorcontrib><creatorcontrib>Roumiguié, M.</creatorcontrib><creatorcontrib>Doumerc, Nicolas</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Immunology Abstracts</collection><collection>ProQuest Health and Medical</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>World journal of urology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Overs, C.</au><au>Beauval, J. B.</au><au>Mourey, L.</au><au>Rischmann, P.</au><au>Soulié, M.</au><au>Roumiguié, M.</au><au>Doumerc, Nicolas</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Robot-assisted post-chemotherapy retroperitoneal lymph node dissection in germ cell tumor: is the single-docking with lateral approach relevant?</atitle><jtitle>World journal of urology</jtitle><stitle>World J Urol</stitle><addtitle>World J Urol</addtitle><date>2018-04-01</date><risdate>2018</risdate><volume>36</volume><issue>4</issue><spage>655</spage><epage>661</epage><pages>655-661</pages><issn>0724-4983</issn><eissn>1433-8726</eissn><abstract>Introduction
Surgical treatment of post-chemotherapy residual mass of germ cell tumor (GCT) may be performed in various techniques. We assess the feasibility, safety, and efficacy of single-docking with lateral approach robot-assisted retroperitoneal lymph node dissection (R-RPLND) in residual mass of GCT in our center.
Materials and methods
A retrospective review of patients undergoing R-RPLND for residual mass of CGT was performed between January 2014 and April 2017. Patients with residual mass < 3 cm for seminoma or < 1 cm for non-seminoma were eligible. All surgeries were performed with single-docking RPNLD technique in lateral decubitus. We assessed preoperative characteristics (age, testicular pathology, template, chemotherapy regimen, lesion size, and clinical stage), peroperative (operative time, estimated blood loss, intraoperative complication, node count, pathology, and number of positive node), and postoperative outcomes (postoperative complications, hospital length of stay, recurrence-free survival at 2 year, and ejaculation dysfunction).
Results
Eleven patients underwent R-RPLND with a median size of the residual mass of 20 mm. Median operative time was 153 min with 120 ml of estimated blood loss, without intraoperative complication. Median nodes count was 7 [1; 24]. Two patients had post-chemotherapy necrotic nodes and one no tumorous node. One patient had postoperative Clavien I complication (chyloperitoneum). We report 72.7% of antegrade ejaculation at 1 month from the surgery. Median clinical recurrence-free survival was 100% after 2 years from the surgery (
n
= 6).
Conclusion
Lateral approach with single-docking R-RPLND for residual mass of GCT is feasible and safe, with satisfying functional and oncologic outcomes.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>29353314</pmid><doi>10.1007/s00345-018-2177-y</doi><tpages>7</tpages></addata></record> |
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| subjects | Adult Biopsy Chemotherapy Disease-Free Survival Ejaculation Feasibility Studies France Humans Lymph Lymph Node Excision - adverse effects Lymph Node Excision - methods Lymph nodes Lymph Nodes - diagnostic imaging Lymph Nodes - pathology Lymph Nodes - surgery Lymphatic Metastasis Lymphatic system Male Medicine Medicine & Public Health Middle Aged Neoplasm Staging Neoplasms, Germ Cell and Embryonal - pathology Neoplasms, Germ Cell and Embryonal - radiotherapy Nephrology Oncology Original Article Outcome and Process Assessment (Health Care) Postoperative Complications - diagnosis Postoperative Complications - epidemiology Retroperitoneal Space Robotic surgery Robotic Surgical Procedures - adverse effects Robotic Surgical Procedures - methods Seminoma Seminoma - pathology Seminoma - radiotherapy Testicular cancer Testicular Neoplasms - pathology Testicular Neoplasms - radiotherapy Urology |
| title | Robot-assisted post-chemotherapy retroperitoneal lymph node dissection in germ cell tumor: is the single-docking with lateral approach relevant? |
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