Five New Alkaloids from the Roots of Sophora flavescens

Five new quinolizidine alkaloids, including three sparteine‐type alkaloids (1 – 3) and two cytisine‐type alkaloids (4 and 5), along with four known ones, were isolated from the roots of Sophora flavescens. Their structures were determined by extensive spectroscopic techniques including IR, UV, NMR,...

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Bibliographic Details
Published in:Chemistry & biodiversity 2018-03, Vol.15 (3), p.e1700577-n/a
Main Authors: Zhang, Sheng‐Yuan, Li, Wen, Nie, Hua, Liao, Mei, Qiu, Bo, Yang, Ya‐Li, Chen, Yan‐Fen
Format: Article
Language:English
Subjects:
Alkaloids
antibacterial activities
cytisine‐type alkaloids
E coli
NMR
Nuclear magnetic resonance
quinolizidine alkaloids
Roots
Sophora flavescens
sparteine‐type alkaloids
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Summary:Five new quinolizidine alkaloids, including three sparteine‐type alkaloids (1 – 3) and two cytisine‐type alkaloids (4 and 5), along with four known ones, were isolated from the roots of Sophora flavescens. Their structures were determined by extensive spectroscopic techniques including IR, UV, NMR, and HR‐ESI‐MS. All the compounds were evaluated for their antibacterial activities against Staphylococcus aureus and Escherichia coli.
ISSN:1612-1872
1612-1880
DOI:10.1002/cbdv.201700577