Evaluation of transient elastography in assessing liver fibrosis in patients with advanced schistosomiasis japonica

Schistosomiasis remains an important public health issue. The presence and extent of liver fibrosis are associated with disease progression and prognosis. The study is aimed at exploring the value of liver stiffness measurement (LSM) by transient elastography in assessing liver fibrosis in patients...

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Bibliographic Details
Published in:Parasitology international 2018-06, Vol.67 (3), p.302-308
Main Authors: Wu, Shengdi, Tseng, Yujen, Xu, Nuo, Yin, Xinguang, Xie, Xinsheng, Zhang, Lifang, Wu, Wanxin, Zhu, Wenjun, Wu, Wenlin, Yao, Jiankang, Wu, Yiming
Format: Article
Language:English
Subjects:
Advanced schistosomiasis japonica
Liver fibrosis
Liver stiffness measurement
Noninvasive
Transient elastography
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Summary:Schistosomiasis remains an important public health issue. The presence and extent of liver fibrosis are associated with disease progression and prognosis. The study is aimed at exploring the value of liver stiffness measurement (LSM) by transient elastography in assessing liver fibrosis in patients with advanced schistosomiasis japonica. Seventy-three patients were consecutively recruited for the purpose of this study. The correlation between noninvasive parameters and histological fibrosis stages was analyzed and an area under receiver operating characteristic curve (AUROC) was used to assess diagnostic efficacy. Our results demonstrated that there are significant differences between LSM values of patients with different stages of fibrosis (F1 vs. F2, F2 vs. F3 and F3 vs. F4, P
ISSN:1383-5769
1873-0329
DOI:10.1016/j.parint.2018.01.004