Risk Factors for Hidradenitis Suppurativa in Patients with Inflammatory Bowel Disease

Background Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder characterized by recurrent nodules, abscesses, and sinus tracts that can be debilitating and significantly impair quality of life. Small studies and case reports have suggested a possible association between HS and infl...

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Bibliographic Details
Published in:Digestive diseases and sciences 2018-03, Vol.63 (3), p.755-760
Main Authors: Lukach, Alexis J., Saul, Melissa I., Ferris, Laura K., Swoger, Jason M.
Format: Article
Language:English
Subjects:
Biochemistry
Gastroenterology
Hepatology
Inflammatory bowel disease
Medical colleges
Medical records
Medical research
Medicine
Medicine & Public Health
Medicine, Experimental
Oncology
Original Article
Risk factors
Skin
Transplant Surgery
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Summary:Background Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder characterized by recurrent nodules, abscesses, and sinus tracts that can be debilitating and significantly impair quality of life. Small studies and case reports have suggested a possible association between HS and inflammatory bowel disease (IBD). Aims We performed a case–control study to further characterize IBD patients with HS in terms of smoking status, BMI, sites affected by HS, IBD type and features, and IBD medication history. Methods A total of 38 patients with HS and IBD were identified and matched on age, gender, and IBD type to 136 controls with IBD but not HS. Clinical characteristics of interest were obtained through extensive review of the electronic health record. Results Among patients with HS and IBD, the most common sites affected by HS were the inguinal, perianal, and axillary regions. Relative to patients with IBD alone, patients with HS and IBD were nearly six times more likely to be current smokers ( p  
ISSN:0163-2116
1573-2568
DOI:10.1007/s10620-018-4919-5