Gold nanoparticles in delivery applications

Gold nanoparticles (AuNPs) provide non-toxic carriers for drug and gene delivery applications. With these systems, the gold core imparts stability to the assembly, while the monolayer allows tuning of surface properties such as charge and hydrophobicity. An additional attractive feature of AuNPs is...

Full description

Saved in:
Bibliographic Details
Published in:Advanced drug delivery reviews 2008-08, Vol.60 (11), p.1307-1315
Main Authors: Ghosh, Partha, Han, Gang, De, Mrinmoy, Kim, Chae Kyu, Rotello, Vincent M.
Format: Article
Language:English
Subjects:
Animals
Delivery
DNA
Drug delivery
Drug Delivery Systems - methods
Gene Transfer Techniques
Glutathione
Gold
Gold - chemistry
Humans
Metal Nanoparticles - chemistry
Nanoparticles
Photochemistry
Release
Self-assembled monolayer
Sulfhydryl Compounds - metabolism
Temperature
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Gold nanoparticles (AuNPs) provide non-toxic carriers for drug and gene delivery applications. With these systems, the gold core imparts stability to the assembly, while the monolayer allows tuning of surface properties such as charge and hydrophobicity. An additional attractive feature of AuNPs is their interaction with thiols, providing an effective and selective means of controlled intracellular release.
ISSN:0169-409X
1872-8294
DOI:10.1016/j.addr.2008.03.016