Gold nanoparticles in delivery applications

Gold nanoparticles (AuNPs) provide non-toxic carriers for drug and gene delivery applications. With these systems, the gold core imparts stability to the assembly, while the monolayer allows tuning of surface properties such as charge and hydrophobicity. An additional attractive feature of AuNPs is...

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Published in:Advanced drug delivery reviews 2008-08, Vol.60 (11), p.1307-1315
Main Authors: Ghosh, Partha, Han, Gang, De, Mrinmoy, Kim, Chae Kyu, Rotello, Vincent M.
Format: Article
Language:English
Subjects:
Animals
Delivery
DNA
Drug delivery
Drug Delivery Systems - methods
Gene Transfer Techniques
Glutathione
Gold
Gold - chemistry
Humans
Metal Nanoparticles - chemistry
Nanoparticles
Photochemistry
Release
Self-assembled monolayer
Sulfhydryl Compounds - metabolism
Temperature
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container_end_page 1315
container_issue 11
container_start_page 1307
container_title Advanced drug delivery reviews
container_volume 60
creator Ghosh, Partha
Han, Gang
De, Mrinmoy
Kim, Chae Kyu
Rotello, Vincent M.
description Gold nanoparticles (AuNPs) provide non-toxic carriers for drug and gene delivery applications. With these systems, the gold core imparts stability to the assembly, while the monolayer allows tuning of surface properties such as charge and hydrophobicity. An additional attractive feature of AuNPs is their interaction with thiols, providing an effective and selective means of controlled intracellular release.
doi_str_mv 10.1016/j.addr.2008.03.016
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source ScienceDirect Journals
subjects Animals
Delivery
DNA
Drug delivery
Drug Delivery Systems - methods
Gene Transfer Techniques
Glutathione
Gold
Gold - chemistry
Humans
Metal Nanoparticles - chemistry
Nanoparticles
Photochemistry
Release
Self-assembled monolayer
Sulfhydryl Compounds - metabolism
Temperature
title Gold nanoparticles in delivery applications
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