Exophiala dermatitidis Endophthalmitis: Case Report and Literature Review

We report a case of a 59-year-old male patient with a postoperative fungal infection of the left eye. A dark-pigmented yeast, Exophiala dermatitidis (previously known as Wangiella dermatitidis ), was identified from the culture of the biopsy taken from the posterior capsule. The infection was succes...

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Bibliographic Details
Published in:Mycopathologia (1975) 2018-06, Vol.183 (3), p.603-609
Main Authors: Homa, Mónika, Manikandan, Palanisamy, Saravanan, Veerappan, Revathi, Rajaraman, Anita, Raghavan, Narendran, Venkatapathy, Panneerselvam, Kanesan, Shobana, Coimbatore Subramanian, Aidarous, Mohammed Al, Galgóczy, László, Vágvölgyi, Csaba, Papp, Tamás, Kredics, László
Format: Article
Language:English
Subjects:
Antifungal Agents - administration & dosage
Biomedical and Life Sciences
Biopsy
Case reports
Debridement
Endophthalmitis
Endophthalmitis - diagnosis
Endophthalmitis - microbiology
Endophthalmitis - pathology
Endophthalmitis - therapy
Eukaryotic Microbiology
Exophiala - isolation & purification
Fluconazole
Fungicides
Health aspects
Humans
Infection
Infections
Life Sciences
Literature reviews
Male
Medical Microbiology
Microbial Ecology
Microbiological Techniques
Microbiology
Middle Aged
Mycoses
Phaeohyphomycosis - diagnosis
Phaeohyphomycosis - microbiology
Phaeohyphomycosis - pathology
Phaeohyphomycosis - therapy
Pigments, Biological - analysis
Plant Sciences
Short Communication
Surgical Wound Infection - diagnosis
Surgical Wound Infection - microbiology
Surgical Wound Infection - pathology
Surgical Wound Infection - therapy
Treatment Outcome
Voriconazole
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Summary:We report a case of a 59-year-old male patient with a postoperative fungal infection of the left eye. A dark-pigmented yeast, Exophiala dermatitidis (previously known as Wangiella dermatitidis ), was identified from the culture of the biopsy taken from the posterior capsule. The infection was successfully eradicated by a combination of surgical and medical (i.e., voriconazole and fluconazole) treatment. This is the first report of successfully treated E. dermatitidis endophthalmitis, which demonstrates that a prompt and aggressive antifungal therapy combined with surgical intervention is necessary to prevent vision loss in cases of endophthalmitis due to Exophiala species. Beside the case description, we also aim to provide a literature review of previously reported eye infections caused by Exophiala species in order to help the future diagnosis and management of the disease.
ISSN:0301-486X
1573-0832
DOI:10.1007/s11046-017-0235-4