Clinical Assessment of Micro-residual Tumors during Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma

This study aimed to assess the need to consider microscopic invasion in terms of treatment planning in stereotactic body radiation therapy (SBRT) for hepatocellular carcinoma and elucidate the appropriate clinical target volume (CTV) margin. A total of 121 patients (with 146 liver tumors) who underw...

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Bibliographic Details
Published in:Anticancer research 2018-02, Vol.38 (2), p.945-954
Main Authors: Uemoto, Kenji, Doi, Hiroshi, Shiomi, Hiroya, Yamada, Koichi, Tatsumi, Daisaku, Yasumoto, Taku, Takashina, Masaaki, Koizumi, Masahiko, Oh, Ryoong-Jin
Format: Article
Language:English
Subjects:
Background radiation
Hepatocellular carcinoma
Liver
Liver cancer
Patients
Radiation
Radiation therapy
Tumors
α-Fetoprotein
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Summary:This study aimed to assess the need to consider microscopic invasion in terms of treatment planning in stereotactic body radiation therapy (SBRT) for hepatocellular carcinoma and elucidate the appropriate clinical target volume (CTV) margin. A total of 121 patients (with 146 liver tumors) who underwent SBRT between July 2007 and August 2016 were analyzed, regarding overall survival and local control (LC). The 2- and 5-year LC rates were 91.5% and 89.8%, respectively. Planning target volume (PTV) margin
ISSN:0250-7005
1791-7530
DOI:10.21873/anticanres.12308