Potential of solid state fermentation for production of ergot alkaloids

Production of total ergot alkaloids by Claviceps fusiformis in solid state fermentation was 3.9 times higher compared to that in submerged fermentation. Production was equal in the case of Claviceps purpurea but the spectra of alkaloids were advantageous with the use of solid state fermentation. The...

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Bibliographic Details
Published in:Letters in applied microbiology 1992-10, Vol.15 (4), p.156-159
Main Authors: Trejo Hernandez, M.R, Raimbault, M, Roussos, S, Lonsane, B.K
Format: Article
Language:English
Subjects:
Biological and medical sciences
biosynthesis
Biotechnology
Claviceps fusiformis
Claviceps purpurea
ergometrine
ergot alkaloids
ergotamine
fermentation
Fundamental and applied biological sciences. Psychology
Health. Pharmaceutical industry
Industrial applications and implications. Economical aspects
lysergic acid derivatives
lysergol
sugarcane bagasse
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Summary:Production of total ergot alkaloids by Claviceps fusiformis in solid state fermentation was 3.9 times higher compared to that in submerged fermentation. Production was equal in the case of Claviceps purpurea but the spectra of alkaloids were advantageous with the use of solid state fermentation. The data establish potential of solid state fermentation which was not explored earlier for production of ergot alkaloids.
ISSN:0266-8254
1472-765X
DOI:10.1111/j.1472-765x.1992.tb00751.x