Do Quiescent Human Peripheral Lymphocytes Repair Radiation-Induced Chromosome Damage?

Kondrashova, T.V. and Ivanova, T.I. Do Quiescent Human Peripheral Lymphocytes Repair Radiation-Induced Chromosome Damage? Peripheral blood samples from seven healthy donors were exposed to 2 Gy of60Co gamma rays. Lymphocyte cultures were prepared from the samples and stimulated to proliferate either...

Full description

Saved in:
Bibliographic Details
Published in:Radiation research 2000-01, Vol.153 (1), p.122-124
Main Authors: Kondrashova, T V, Ivanova, TI
Format: Article
Language:English
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites
container_end_page 124
container_issue 1
container_start_page 122
container_title Radiation research
container_volume 153
creator Kondrashova, T V
Ivanova, TI
description Kondrashova, T.V. and Ivanova, T.I. Do Quiescent Human Peripheral Lymphocytes Repair Radiation-Induced Chromosome Damage? Peripheral blood samples from seven healthy donors were exposed to 2 Gy of60Co gamma rays. Lymphocyte cultures were prepared from the samples and stimulated to proliferate either immediately after the exposure or after 1, 2 or 4 h. No significant differences were found between the frequencies of chromosome aberrations (breaks or exchange) observed in lymphocytes stimulated after different postirradiation periods. We conclude that unstimulated lymphocytes do not undergo significant levels of recovery from potentially lethal damage at the chromosomal level.
doi_str_mv 10.1043/0033-7587(2000)153<0122:DQHPLR>2.0.CO;2
format article
fullrecord <record><control><sourceid>proquest</sourceid><recordid>TN_cdi_proquest_miscellaneous_19940053</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>19940053</sourcerecordid><originalsourceid>FETCH-proquest_miscellaneous_199400533</originalsourceid><addsrcrecordid>eNqNzb1OwzAUQGEPRaL8vIOnCoak13bTEkAwJKAgVaKNYK6ukltiFNvBjoe-fTsgZqazfNJhbC4gFbBQcwClklV2t7qRAHArMvUIQsr7cltt1vWTTCEt3h_khE3_5Dm7COH7pJVY5lP2WTq-jZpCQ3bkVTRo-Ya8Hjry2PP1wQydaw4jBV7TgNrzGluNo3Y2ebNtbKjlReedccEZ4iUa_KLnK3a2xz7Q9W8v2ez15aOoksG7n0hh3Bl9OvY9WnIx7ESeLwAypf4Nj02CTZE</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>19940053</pqid></control><display><type>article</type><title>Do Quiescent Human Peripheral Lymphocytes Repair Radiation-Induced Chromosome Damage?</title><source>JSTOR Archival Journals and Primary Sources Collection</source><creator>Kondrashova, T V ; Ivanova, TI</creator><creatorcontrib>Kondrashova, T V ; Ivanova, TI</creatorcontrib><description>Kondrashova, T.V. and Ivanova, T.I. Do Quiescent Human Peripheral Lymphocytes Repair Radiation-Induced Chromosome Damage? Peripheral blood samples from seven healthy donors were exposed to 2 Gy of60Co gamma rays. Lymphocyte cultures were prepared from the samples and stimulated to proliferate either immediately after the exposure or after 1, 2 or 4 h. No significant differences were found between the frequencies of chromosome aberrations (breaks or exchange) observed in lymphocytes stimulated after different postirradiation periods. We conclude that unstimulated lymphocytes do not undergo significant levels of recovery from potentially lethal damage at the chromosomal level.</description><identifier>ISSN: 0033-7587</identifier><identifier>DOI: 10.1043/0033-7587(2000)153&lt;0122:DQHPLR&gt;2.0.CO;2</identifier><language>eng</language><ispartof>Radiation research, 2000-01, Vol.153 (1), p.122-124</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Kondrashova, T V</creatorcontrib><creatorcontrib>Ivanova, TI</creatorcontrib><title>Do Quiescent Human Peripheral Lymphocytes Repair Radiation-Induced Chromosome Damage?</title><title>Radiation research</title><description>Kondrashova, T.V. and Ivanova, T.I. Do Quiescent Human Peripheral Lymphocytes Repair Radiation-Induced Chromosome Damage? Peripheral blood samples from seven healthy donors were exposed to 2 Gy of60Co gamma rays. Lymphocyte cultures were prepared from the samples and stimulated to proliferate either immediately after the exposure or after 1, 2 or 4 h. No significant differences were found between the frequencies of chromosome aberrations (breaks or exchange) observed in lymphocytes stimulated after different postirradiation periods. We conclude that unstimulated lymphocytes do not undergo significant levels of recovery from potentially lethal damage at the chromosomal level.</description><issn>0033-7587</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><recordid>eNqNzb1OwzAUQGEPRaL8vIOnCoak13bTEkAwJKAgVaKNYK6ukltiFNvBjoe-fTsgZqazfNJhbC4gFbBQcwClklV2t7qRAHArMvUIQsr7cltt1vWTTCEt3h_khE3_5Dm7COH7pJVY5lP2WTq-jZpCQ3bkVTRo-Ya8Hjry2PP1wQydaw4jBV7TgNrzGluNo3Y2ebNtbKjlReedccEZ4iUa_KLnK3a2xz7Q9W8v2ez15aOoksG7n0hh3Bl9OvY9WnIx7ESeLwAypf4Nj02CTZE</recordid><startdate>20000101</startdate><enddate>20000101</enddate><creator>Kondrashova, T V</creator><creator>Ivanova, TI</creator><scope>7T5</scope><scope>8FD</scope><scope>FR3</scope><scope>H94</scope><scope>P64</scope><scope>RC3</scope></search><sort><creationdate>20000101</creationdate><title>Do Quiescent Human Peripheral Lymphocytes Repair Radiation-Induced Chromosome Damage?</title><author>Kondrashova, T V ; Ivanova, TI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-proquest_miscellaneous_199400533</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kondrashova, T V</creatorcontrib><creatorcontrib>Ivanova, TI</creatorcontrib><collection>Immunology Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><jtitle>Radiation research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kondrashova, T V</au><au>Ivanova, TI</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Do Quiescent Human Peripheral Lymphocytes Repair Radiation-Induced Chromosome Damage?</atitle><jtitle>Radiation research</jtitle><date>2000-01-01</date><risdate>2000</risdate><volume>153</volume><issue>1</issue><spage>122</spage><epage>124</epage><pages>122-124</pages><issn>0033-7587</issn><abstract>Kondrashova, T.V. and Ivanova, T.I. Do Quiescent Human Peripheral Lymphocytes Repair Radiation-Induced Chromosome Damage? Peripheral blood samples from seven healthy donors were exposed to 2 Gy of60Co gamma rays. Lymphocyte cultures were prepared from the samples and stimulated to proliferate either immediately after the exposure or after 1, 2 or 4 h. No significant differences were found between the frequencies of chromosome aberrations (breaks or exchange) observed in lymphocytes stimulated after different postirradiation periods. We conclude that unstimulated lymphocytes do not undergo significant levels of recovery from potentially lethal damage at the chromosomal level.</abstract><doi>10.1043/0033-7587(2000)153&lt;0122:DQHPLR&gt;2.0.CO;2</doi></addata></record>
fulltext fulltext
identifier ISSN: 0033-7587
ispartof Radiation research, 2000-01, Vol.153 (1), p.122-124
issn 0033-7587
language eng
recordid cdi_proquest_miscellaneous_19940053
source JSTOR Archival Journals and Primary Sources Collection
title Do Quiescent Human Peripheral Lymphocytes Repair Radiation-Induced Chromosome Damage?
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-02T19%3A42%3A55IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Do%20Quiescent%20Human%20Peripheral%20Lymphocytes%20Repair%20Radiation-Induced%20Chromosome%20Damage?&rft.jtitle=Radiation%20research&rft.au=Kondrashova,%20T%20V&rft.date=2000-01-01&rft.volume=153&rft.issue=1&rft.spage=122&rft.epage=124&rft.pages=122-124&rft.issn=0033-7587&rft_id=info:doi/10.1043/0033-7587(2000)153%3C0122:DQHPLR%3E2.0.CO;2&rft_dat=%3Cproquest%3E19940053%3C/proquest%3E%3Cgrp_id%3Ecdi_FETCH-proquest_miscellaneous_199400533%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=19940053&rft_id=info:pmid/&rfr_iscdi=true