Potent Antiscrapie Activities of Degenerate Phosphorothioate Oligonucleotides

• Published in: Antimicrobial Agents and Chemotherapy 2006-03, Vol.50 (3), p.1034-1044
• Main Authors: KOCISKO, David A, VAILLANT, Andrew, KIL SUN LEE, ARNOLD, Kevin M, BERTHOLET, Nadine, RACE, Richard E, OLSEN, Emily A, JUTEAU, Jean-Marc, CAUGHEY, Byron
• Format: Article
• Language: English
• Subjects: Animals; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antiviral Agents; Base Composition; Biological and medical sciences; Cell Line; Cricetinae; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; Injections, Intraperitoneal; Injections, Subcutaneous; Medical sciences; Mice; Mice, Transgenic; Molecular Weight; Nucleic Acid Conformation; Oligonucleotides; Oligonucleotides - administration & dosage; Oligonucleotides - chemistry; Oligonucleotides - pharmacology; Pharmacology. Drug treatments; Phosphates; Phosphates - chemistry; PrPSc Proteins; PrPSc Proteins - antagonists & inhibitors; PrPSc Proteins - genetics; Scrapie; Scrapie - metabolism; Scrapie - prevention & control; Survival
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/aac.50.3.1034-1044.2006

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