Composition and larvicidal activity of leaves and stem essential oils of Chloroxylon swietenia DC against Aedes aegypti and Anopheles stephensi

• Published in: Bioresource technology 2006-12, Vol.97 (18), p.2481-2484
• Main Authors: Ravi Kiran, S., Bhavani, K., Sita Devi, P., Rajeswara Rao, B.R., Janardhan Reddy, K.
• Format: Article
• Language: English
• Subjects: Aedes - drug effects; Aedes aegypti; Animals; Anopheles - drug effects; Anopheles stephensi; Biological and medical sciences; Chloroxylon swietenia; Culicidae; Essential oil composition; Fundamental and applied biological sciences. Psychology; Insecticides - analysis; Larva - drug effects; Lethal Dose 50; Medically important nuisances and vectors, pests of stored products and materials: population survey and control; Oils, Volatile - chemistry; Oils, Volatile - pharmacology; Plant Leaves - chemistry; Plant Stems - chemistry; Pregeijerene; Rutaceae - chemistry; Sesquiterpenes; Sesquiterpenes - isolation & purification; Swietenia
• ISSN: 0960-8524; 1873-2976
• DOI: 10.1016/j.biortech.2005.10.003

The laboratory bioassay of the essential oil and the isolated compounds from Chloroxylon swietenia against Aedes aegypti and Anopheles stephensi was carried out to evaluate the larvicidal activity. LC 50 value estimated for A. aegypti and An. stephensi were 16.5 and 14.9 μg/ml and 20.2 and 19 μg/ml for leaf and stem oils, respectively. The three sesquiterpenes pregeijerene, geijerene and germacrene D were isolated and their Larvicidal activity was evaluated. Pregeijerene and geijerene were observed for the first time in the volatile constituents of C. swietenia, however, leaves contained higher amount of geijerene compared to stems.