Referenced MR thermometry using three-echo phase-based fat water separation method

A three-point image reconstruction method for internally referenced MR thermometry was developed. The technique exploits the fact that temperature-induced changes in the water resonance frequency are small relative to the chemical shift difference between water and fat signals. This property enabled...

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Bibliographic Details
Published in:Magnetic resonance imaging 2018-06, Vol.49, p.86-93
Main Authors: Hofstetter, Lorne W., Yeo, Desmond T.B., Dixon, W. Thomas, Marinelli, Luca, Foo, Thomas K.
Format: Article
Language:English
Subjects:
Chemical shift imaging
Computer Simulation
Dairy Products - analysis
Ethylene Glycol - analysis
Fat-referenced
Fats - analysis
Image Processing, Computer-Assisted - methods
Magnetic Resonance Imaging - methods
MR thermometry
Phantoms, Imaging
Temperature mapping
Thermometry - methods
Water - analysis
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Summary:A three-point image reconstruction method for internally referenced MR thermometry was developed. The technique exploits the fact that temperature-induced changes in the water resonance frequency are small relative to the chemical shift difference between water and fat signals. This property enabled the use of small angle approximations to derive an analytic phase-based fat-water separation method for MR thermometry. Ethylene glycol and cream cool-down experiments were performed to validate measurement technique. Over a cool-down temperature range of 20 °C, maximum deviation between probe and MR measurement (averaged over 1.3 cm3 region surrounding probe) was 0.6 °C and 1.1 °C for ethylene glycol and cream samples, respectively.
ISSN:0730-725X
1873-5894
DOI:10.1016/j.mri.2018.01.002