Incidence, risk factors, and outcomes related with neurological events after liver transplantation in adult and pediatric recipients

Controversy exists whether NE after LT are more frequently observed in children or adults. We aimed to compare the incidence and outcomes for NE after LT in pediatric and adult recipients. A single‐center cohort study, including all LT between 2001 and 2013, was performed. Definition of NE included...

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Bibliographic Details
Published in:Pediatric transplantation 2018-05, Vol.22 (3), p.e13159-n/a
Main Authors: Piñero, Federico, Cheang, Yu, Mendizabal, Manuel, Cagliani, Joaquín, Gonzalez Campaña, Ariel, Pages, Josefina, Colaci, Carla, Barreiro, Mariano, Alonso, Cristina, Malla, Ivone, Fauda, Martín, Bueri, Jose, Podesta, Luis G, Silva, Marcelo
Format: Article
Language:English
Subjects:
Adults
adverse events
Ascites
Children
Encephalopathy
Hypomagnesemia
immunosuppression
Liver transplantation
Liver transplants
nervous system
Pediatrics
Risk factors
Seizures
Sodium
transplantation
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Summary:Controversy exists whether NE after LT are more frequently observed in children or adults. We aimed to compare the incidence and outcomes for NE after LT in pediatric and adult recipients. A single‐center cohort study, including all LT between 2001 and 2013, was performed. Definition of NE included impaired consciousness, delirium, seizures, focal neurologic deficit, visual impairment, or slurred speech. A cohort of 443 consecutive LT recipients was included: 307 adults and 136 children. Cumulative incidence of NE was similar between adults 15% (n = 41) and children 16% (n = 20; P = .73) with a complete neurological recovery in 62% and 95% of the patients, respectively (P 
ISSN:1397-3142
1399-3046
DOI:10.1111/petr.13159