Hepatobiliary phase liver MR imaging findings after Oxaliplatin-based chemotherapy in cancer patients

Objective To describe Gd-EOB-DTPA-enhanced liver MR imaging findings in colon and rectal cancer patients who received Oxaliplatin. Conclusion Spectrum of hepatobiliary phase imaging findings include diffuse heterogeneous dysfunction, macronodular and micronodular FNH-like lesions, and coexistence of...

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Bibliographic Details
Published in:Abdominal imaging 2018-09, Vol.43 (9), p.2321-2328
Main Authors: Ünal, Emre, Karaosmanoğlu, Ali Devrim, Ozmen, Mustafa Nasuh, Akata, Deniz, Karcaaltincaba, Musturay
Format: Article
Language:English
Subjects:
Biopsy
Cancer
Chemotherapy
Coexistence
Colon
Colon cancer
Colorectal cancer
Gadolinium
Gastroenterology
Hepatology
Imaging
Lesions
Liver
Magnetic resonance imaging
Medicine
Medicine & Public Health
Metastases
Oxaliplatin
Patients
Pictorial Essay
Radiology
Rectum
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Summary:Objective To describe Gd-EOB-DTPA-enhanced liver MR imaging findings in colon and rectal cancer patients who received Oxaliplatin. Conclusion Spectrum of hepatobiliary phase imaging findings include diffuse heterogeneous dysfunction, macronodular and micronodular FNH-like lesions, and coexistence of periportal increased liver function with FNH-like lesions. Differentiation of these benign lesions from metastasis is crucial to avoid biopsy in patients with colorectal cancers and may allow better understanding of sinusoidal obstruction syndrome pathophysiology and regenerative response of liver.
ISSN:2366-004X
2366-0058
DOI:10.1007/s00261-018-1482-7