Deep blue dot corneal degeneration: confocal characteristics

Purpose To discuss the clinical features, differential diagnosis and the novel confocal microscopic findings noted in the rare ‘deep blue dot corneal degeneration’. Methods Observational case report. Results Slit-lamp biomicroscopic examination revealed bilateral, numerous, circular to oval discrete...

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Bibliographic Details
Published in:International ophthalmology 2019-03, Vol.39 (3), p.667-669
Main Authors: Selvan, Harathy, Singh, Archita, Tandon, Radhika
Format: Article
Language:English
Subjects:
Confocal microscopy
Cornea
Degeneration
Diagnosis
Differential diagnosis
Elementary school students
Lesions
Medicine
Medicine & Public Health
Microscopy
Ophthalmology
Photo Essay
Stroma
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Summary:Purpose To discuss the clinical features, differential diagnosis and the novel confocal microscopic findings noted in the rare ‘deep blue dot corneal degeneration’. Methods Observational case report. Results Slit-lamp biomicroscopic examination revealed bilateral, numerous, circular to oval discrete blue opacities at the level of deep stroma and fine grey linear opacities at the level of mid to deep stroma. Confocal microscopy demonstrated two types of corresponding hyper-reflective extracellular lesions: oval deposit-like, most concentrated at a depth of 430–480 µ and needle-like at the depth 330–370 µ. Conclusions Deep blue dot corneal degeneration is a rare entity where blue deposits of amyloid are seen in the deep corneal stroma. It should be considered as a differential diagnosis when an old-aged person presents with good vision and the above mentioned findings.
ISSN:0165-5701
1573-2630
DOI:10.1007/s10792-018-0849-7