Population Pharmacokinetics and Pharmacodynamics of Continuous versus Short-Term Infusion of Imipenem-Cilastatin in Critically Ill Patients in a Randomized, Controlled Trial

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Published in:Antimicrobial Agents and Chemotherapy 2007-09, Vol.51 (9), p.3304-3310
Main Authors: SAKKA, Samir G, GLAUNER, Anna K, BULITTA, Jürgen B, KINZIG-SCHIPPERS, Martina, PFISTER, Wolfgang, DRUSANO, George L, SÖRGEL, Fritz
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Analysis of Variance
Anti-Bacterial Agents
Anti-Bacterial Agents - administration & dosage
Anti-Bacterial Agents - pharmacokinetics
Anti-Bacterial Agents - therapeutic use
Antibiotics. Antiinfectious agents. Antiparasitic agents
Biological and medical sciences
Chromatography, High Pressure Liquid
Cilastatin
Cilastatin - administration & dosage
Cilastatin - pharmacokinetics
Cilastatin - therapeutic use
Clinical Therapeutics
Critical Illness
Cross Infection
Cross Infection - drug therapy
Cross Infection - microbiology
Drug Combinations
Female
Humans
Imipenem
Imipenem - administration & dosage
Imipenem - pharmacokinetics
Imipenem - therapeutic use
Infusions, Intravenous
Logistic Models
Male
Medical sciences
Middle Aged
Monte Carlo Method
Pharmacology. Drug treatments
Protease Inhibitors
Protease Inhibitors - administration & dosage
Protease Inhibitors - pharmacokinetics
Protease Inhibitors - therapeutic use
Tandem Mass Spectrometry
Treatment Outcome
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Summary:Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       
ISSN:0066-4804
1098-6596
DOI:10.1128/AAC.01318-06