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Population Pharmacokinetics and Pharmacodynamics of Continuous versus Short-Term Infusion of Imipenem-Cilastatin in Critically Ill Patients in a Randomized, Controlled Trial
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Published in: | Antimicrobial Agents and Chemotherapy 2007-09, Vol.51 (9), p.3304-3310 |
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creator | SAKKA, Samir G GLAUNER, Anna K BULITTA, Jürgen B KINZIG-SCHIPPERS, Martina PFISTER, Wolfgang DRUSANO, George L SÖRGEL, Fritz |
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</description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/AAC.01318-06</identifier><identifier>PMID: 17620371</identifier><identifier>CODEN: AACHAX</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Analysis of Variance ; Anti-Bacterial Agents ; Anti-Bacterial Agents - administration & dosage ; Anti-Bacterial Agents - pharmacokinetics ; Anti-Bacterial Agents - therapeutic use ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Biological and medical sciences ; Chromatography, High Pressure Liquid ; Cilastatin ; Cilastatin - administration & dosage ; Cilastatin - pharmacokinetics ; Cilastatin - therapeutic use ; Clinical Therapeutics ; Critical Illness ; Cross Infection ; Cross Infection - drug therapy ; Cross Infection - microbiology ; Drug Combinations ; Female ; Humans ; Imipenem ; Imipenem - administration & dosage ; Imipenem - pharmacokinetics ; Imipenem - therapeutic use ; Infusions, Intravenous ; Logistic Models ; Male ; Medical sciences ; Middle Aged ; Monte Carlo Method ; Pharmacology. Drug treatments ; Protease Inhibitors ; Protease Inhibitors - administration & dosage ; Protease Inhibitors - pharmacokinetics ; Protease Inhibitors - therapeutic use ; Tandem Mass Spectrometry ; Treatment Outcome</subject><ispartof>Antimicrobial Agents and Chemotherapy, 2007-09, Vol.51 (9), p.3304-3310</ispartof><rights>2007 INIST-CNRS</rights><rights>Copyright © 2007 American Society for Microbiology</rights><rights>Copyright © 2007, American Society for Microbiology 2007</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a546t-112b2fb8b5f5cd23ab07b9493ae8b10587ede749e846d36ada8cb73a6ce62e5d3</citedby><cites>FETCH-LOGICAL-a546t-112b2fb8b5f5cd23ab07b9493ae8b10587ede749e846d36ada8cb73a6ce62e5d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.asm.org/doi/pdf/10.1128/AAC.01318-06$$EPDF$$P50$$Gasm2$$H</linktopdf><linktohtml>$$Uhttps://journals.asm.org/doi/full/10.1128/AAC.01318-06$$EHTML$$P50$$Gasm2$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,3175,3176,27901,27902,52726,52727,52728,53766,53768</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19050229$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17620371$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>SAKKA, Samir G</creatorcontrib><creatorcontrib>GLAUNER, Anna K</creatorcontrib><creatorcontrib>BULITTA, Jürgen B</creatorcontrib><creatorcontrib>KINZIG-SCHIPPERS, Martina</creatorcontrib><creatorcontrib>PFISTER, Wolfgang</creatorcontrib><creatorcontrib>DRUSANO, George L</creatorcontrib><creatorcontrib>SÖRGEL, Fritz</creatorcontrib><title>Population Pharmacokinetics and Pharmacodynamics of Continuous versus Short-Term Infusion of Imipenem-Cilastatin in Critically Ill Patients in a Randomized, Controlled Trial</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>AAC</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Classifications
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</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Analysis of Variance</subject><subject>Anti-Bacterial Agents</subject><subject>Anti-Bacterial Agents - administration & dosage</subject><subject>Anti-Bacterial Agents - pharmacokinetics</subject><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Antibiotics. Antiinfectious agents. 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Antiinfectious agents. Antiparasitic agents</topic><topic>Biological and medical sciences</topic><topic>Chromatography, High Pressure Liquid</topic><topic>Cilastatin</topic><topic>Cilastatin - administration & dosage</topic><topic>Cilastatin - pharmacokinetics</topic><topic>Cilastatin - therapeutic use</topic><topic>Clinical Therapeutics</topic><topic>Critical Illness</topic><topic>Cross Infection</topic><topic>Cross Infection - drug therapy</topic><topic>Cross Infection - microbiology</topic><topic>Drug Combinations</topic><topic>Female</topic><topic>Humans</topic><topic>Imipenem</topic><topic>Imipenem - administration & dosage</topic><topic>Imipenem - pharmacokinetics</topic><topic>Imipenem - therapeutic use</topic><topic>Infusions, Intravenous</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Monte Carlo Method</topic><topic>Pharmacology. 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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>17620371</pmid><doi>10.1128/AAC.01318-06</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Aged Aged, 80 and over Analysis of Variance Anti-Bacterial Agents Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - pharmacokinetics Anti-Bacterial Agents - therapeutic use Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Chromatography, High Pressure Liquid Cilastatin Cilastatin - administration & dosage Cilastatin - pharmacokinetics Cilastatin - therapeutic use Clinical Therapeutics Critical Illness Cross Infection Cross Infection - drug therapy Cross Infection - microbiology Drug Combinations Female Humans Imipenem Imipenem - administration & dosage Imipenem - pharmacokinetics Imipenem - therapeutic use Infusions, Intravenous Logistic Models Male Medical sciences Middle Aged Monte Carlo Method Pharmacology. Drug treatments Protease Inhibitors Protease Inhibitors - administration & dosage Protease Inhibitors - pharmacokinetics Protease Inhibitors - therapeutic use Tandem Mass Spectrometry Treatment Outcome |
title | Population Pharmacokinetics and Pharmacodynamics of Continuous versus Short-Term Infusion of Imipenem-Cilastatin in Critically Ill Patients in a Randomized, Controlled Trial |
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