Influence of body mass index on short-term subjective improvement and risk of reoperation after mid-urethral sling surgery

• Published in: International Urogynecology Journal 2018-04, Vol.29 (4), p.585-591
• Main Authors: Weltz, Vibeke, Guldberg, Rikke, Larsen, Michael D., Magnussen, Bjarne, Lose, Gunnar
• Format: Article
• Language: English
• Subjects: Body mass index; Gynecology; Medicine; Medicine & Public Health; Original Article; Surgery; Urology
• ISSN: 0937-3462; 1433-3023
• DOI: 10.1007/s00192-018-3570-1

Introduction and hypothesis The objective was to evaluate the impact of body mass index (BMI) on the subjective improvement and risk of reoperation after first-time mid-urethral sling surgery. Methods Data were retrieved from the national Danish Urogynaecological Database, including women with first-time surgery with mid-urethral polypropylene slings from 2011 to 2016. The subjective improvement was assessed by the difference in symptoms based on the International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF) completed pre- and 3 months postoperatively. A reoperation was defined as any new surgical procedure for stress urinary incontinence performed within the study period. Results During the study period, 6,414 mid-urethral sling procedures were performed; 80.0% of these women filled out both pre- and post-surgical International Consultation on Incontinence Questionnaire (ICI-Q) forms. 42.4% had a BMI 35. The subjective improvement after surgery was high in all BMI categories and there were no differences between the categories. The overall cumulative hazard proportion at 2 years of follow-up was 1.9% (CI 95%: 1.6–2.3) and after 5 years 2.4% (CI 95%: 2.0–2.9). Adjusted for age, smoking, and use of alcohol, the cumulative hazard proportion after 2 years of follow-up was 3.2% (CI 95%: 1.6–6.2) for women with BMI >35 and after 5 years 4.0% (CI 95%: 2.0–7.7), which was the highest proportion of reoperation in the study. The crude hazard ratio was 1.84 (CI 95%: 0.89–3.83) women with BMI >35 and the adjusted hazard ratio was 1.94 (CI 95%: 0.92–4.09). Conclusions We found high subjective improvement after the first-time surgery unrelated to BMI. Women with a BMI over 35 had the highest proportion of reoperations, although this was not statistically significant.