Peripheral Artery Disease and Continuous Flow Left Ventricle Assist Device: An Engaging Complement Analysis May Help to Guide Treatment

Use of continuous flow left ventricle assist device (CF‐LVAD) in advanced heart failure (HF) patients results in clinically relevant improvements in survival, functional capacity, and quality of life. Peripheral artery disease (PAD) can occur in patients with CF‐LVAD due to the high rate of concomit...

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Bibliographic Details
Published in:Artificial organs 2018-07, Vol.42 (7), p.756-759
Main Authors: Falletta, Calogero, Pasta, Salvatore, Raffa, Giuseppe Maria, Crinò, Francesca, Sciacca, Sergio, Clemenza, Francesco
Format: Article
Language:English
Subjects:
Advanced heart failure
Arteriosclerosis
Atherosclerosis
Blood Flow Velocity
Cardiomyopathies - complications
Cardiomyopathies - physiopathology
Cardiomyopathies - surgery
Cardiomyopathy
Computational flow analysis
Computer applications
Computer simulation
Continuous flow
Data processing
Disturbances
Heart
Heart diseases
Heart Failure - complications
Heart Failure - physiopathology
Heart Failure - surgery
Heart transplantation
Heart Ventricles - physiopathology
Heart Ventricles - surgery
Heart-Assist Devices - adverse effects
Hemodynamics
Humans
Image enhancement
Implantation
Ischemia
Left ventricle assist device
Male
Middle Aged
Morphology
Patients
Peripheral Arterial Disease - etiology
Peripheral Arterial Disease - physiopathology
Peripheral artery disease
Quality of life
Risk analysis
Risk factors
Transplants & implants
Vascular diseases
Ventricle
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Summary:Use of continuous flow left ventricle assist device (CF‐LVAD) in advanced heart failure (HF) patients results in clinically relevant improvements in survival, functional capacity, and quality of life. Peripheral artery disease (PAD) can occur in patients with CF‐LVAD due to the high rate of concomitance between risk factors for atherosclerosis and HF. Diagnosis of PAD can be difficult in the specific setting of a patient supported by this kind of device because of the marked alteration in waveform morphology and velocity created by the artificial physiology of an LVAD. We report the case of a 53‐year‐old man with HF secondary to ischemic cardiomyopathy supported by the HeartWare HVAD as bridge to transplant, who after the implant developed symptoms suggestive of PAD. We describe additional computational flow analysis for the study of PAD‐related hemodynamic disturbances induced by a CF‐LVAD. Flow simulations enhance the information of clinical image data, and may have an application in clinical investigations of the risk of hemodynamic disturbances induced by LVAD implantation.
ISSN:0160-564X
1525-1594
DOI:10.1111/aor.13105