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The serum concentrations of perfluoroalkyl compounds were inversely associated with growth parameters in 2-year old children

The relationship between the serum concentrations of perfluoroalkyl compounds (PFCs) and growth parameters was investigated in 2-year-old Korean children. The study included 361 children aged 2years (192 boys and 169 girls; 22–27months), born at term appropriate-for-gestational-age, who visited betw...

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Bibliographic Details
Published in:The Science of the total environment 2018-07, Vol.628-629, p.226-232
Main Authors: Lee, Young Ah, Kim, Jin Hee, Jung, Hae Woon, Lim, Youn-Hee, Bae, Sanghyuk, Kho, Younglim, Hong, Yun-Chul, Shin, Choong Ho, Yang, Sei Won
Format: Article
Language:English
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Summary:The relationship between the serum concentrations of perfluoroalkyl compounds (PFCs) and growth parameters was investigated in 2-year-old Korean children. The study included 361 children aged 2years (192 boys and 169 girls; 22–27months), born at term appropriate-for-gestational-age, who visited between 2012 and 2013. Growth parameters of height and weight, and serum samples were collected from 2-year-old children. Four PFCs (perfluorohexane sulfonic acid [PFHxS], perfluorooctane sulfonic acid [PFOS], perfluorooctanoic acid [PFOA], and perfluorononanoic acid [PFNA]), perfluorodecanoic acid (PFDA), perfluoroundecanoic acid (PFUnDA), and perfluoroheptanoic acid (PFHpA) were detected in >99, 93.4, 89.8, and 74.2% of the serum samples, respectively. The duration of breastfeeding was positively associated with the serum concentrations of ln-transformed PFHxS, PFOS, PFHpA, PFOA, PFNA, PFDA, and PFUnDA (all P90% of serum samples from 2-year-old Korean children.•The duration of breastfeeding was positively associated with serum concentrations of perfluoroalkyl compounds in 2-year-old children.•The serum concentrations of perfluoroalkyl compounds were inversely associated with growth parameters in 2-year-old children.
ISSN:0048-9697
1879-1026
DOI:10.1016/j.scitotenv.2018.02.050