Thrombelastography Suggests Hypercoagulability in Patients with Renal Dysfunction and Intracerebral Hemorrhage

The objective of this study was to quantify coagulopathy using thrombelastography (TEG) in patients with renal dysfunction and intracerebral hemorrhage (ICH). We reviewed patients admitted with spontaneous ICH between November 2009 and May 2015. TEG was performed at the time of admission. Creatinine...

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Bibliographic Details
Published in:Journal of stroke and cerebrovascular diseases 2018-05, Vol.27 (5), p.1350-1356
Main Authors: Meier, Kevin, Saenz, Daniel M., Torres, Glenda L., Cai, Chunyan, Rahbar, Mohammed H., McDonald, Mark, Fraser, Stuart, Espino, Elena, Choi, H. Alex, Edwards, Nancy J., Lee, Kiwon, Grotta, James C., Chang, Tiffany R.
Format: Article
Language:English
Subjects:
acute kidney injury
Adult
Aged
Biomarkers - blood
Blood Coagulation
Cerebral Hemorrhage - blood
Cerebral Hemorrhage - complications
Cerebral Hemorrhage - diagnosis
Cerebral Hemorrhage - mortality
Chi-Square Distribution
coagulation
Creatinine - blood
Female
Glomerular Filtration Rate
Humans
intracerebral hemorrhage
Kidney - physiopathology
kidney disease
Kidney Diseases - complications
Kidney Diseases - diagnosis
Kidney Diseases - mortality
Kidney Diseases - physiopathology
Male
Middle Aged
Multivariate Analysis
Predictive Value of Tests
Risk Factors
stroke
Thombelastography
Thrombelastography
Thrombophilia - blood
Thrombophilia - complications
Thrombophilia - diagnosis
Thrombophilia - mortality
uremia
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Summary:The objective of this study was to quantify coagulopathy using thrombelastography (TEG) in patients with renal dysfunction and intracerebral hemorrhage (ICH). We reviewed patients admitted with spontaneous ICH between November 2009 and May 2015. TEG was performed at the time of admission. Creatinine clearance (CCr) was calculated using the Cockroft–Gault equation. Patients were divided into 2 groups based on normal (CCr ≥ 90) or reduced renal function (CCr 
ISSN:1052-3057
1532-8511
DOI:10.1016/j.jstrokecerebrovasdis.2017.12.026