Validation of acute kidney injury according to the modified KDIGO criteria in infants after cardiac surgery for congenital heart disease

ABSTRACT Aim We aimed to validate the incidence of, risk factors for, and postoperative outcomes of acute kidney injury (AKI) according to the modified Kidney Disease Improving Global Outcomes (m‐KDIGO) criteria and compare this criteria with both the paediatric Risk, Injury, Failure, Loss, End‐stag...

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Bibliographic Details
Published in:Nephrology (Carlton, Vic.) Vic.), 2019-03, Vol.24 (3), p.294-300
Main Authors: Ueno, Kentaro, Seki, Shunji, Shiokawa, Naohiro, Matsuba, Tomoyuki, Miyazono, Akinori, Hazeki, Daisuke, Imoto, Yutaka, Kawano, Yoshifumi
Format: Article
Language:English
Subjects:
acute kidney injury
Body weight
cardiac surgery
congenital heart disease
Coronary artery disease
Heart diseases
Heart surgery
infant
Infants
Kidney diseases
Kidneys
m‐KDIGO criteria
Postoperative period
Risk factors
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Summary:ABSTRACT Aim We aimed to validate the incidence of, risk factors for, and postoperative outcomes of acute kidney injury (AKI) according to the modified Kidney Disease Improving Global Outcomes (m‐KDIGO) criteria and compare this criteria with both the paediatric Risk, Injury, Failure, Loss, End‐stage disease (pRIFLE) and Acute Kidney Injury Network (AKIN) criteria in infants after cardiac surgery. Methods We retrospectively enrolled 145 consecutive infants who underwent open‐heart surgery at Kagoshima University Hospital. Results Acute kidney injury was present in 55 (37.9%), 111 (75.9%), and 95 (65.5%) patients according to the m‐KDIGO, pRIFLE, and AKIN criteria, respectively. Among these, 71.9% of patients pRIFLE Risk patients and 60.5% of AKIN 1 patients were categorized in the ‘no‐AKI’ group according to the m‐KDIGO criteria. Low body weight (m‐KDIGO odds ratio [OR], 0.73; P = 0.015; pRIFLE OR, 0.66; P = 0.001; AKIN OR 0.69, P = 0.002) and prolonged cross‐clamp time (m‐KDIGO OR, 1.02;
ISSN:1320-5358
1440-1797
DOI:10.1111/nep.13240