Factors predictive of the onset and duration of action of local anesthesia in mandibular third‐molar surgery: a prospective study

The aim of this study was to assess the influence of patients' and surgical variables on the onset and duration of action of local anesthesia (LA) in mandibular third‐molar (M3) surgery. Patients scheduled for mandibular M3 surgery were considered for inclusion in this prospective cohort study....

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Bibliographic Details
Published in:European journal of oral sciences 2018-04, Vol.126 (2), p.110-117
Main Authors: Al‐Shayyab, Mohammad H., Baqain, Zaid H.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age
Aged
Analysis of Variance
Anesthesia
Anesthesia, Dental
Anesthesia, Local
Body mass
Body mass index
Body size
Cigarette Smoking
Data processing
Dentistry
Epinephrine
Female
Humans
Lidocaine
Local anesthesia
Male
Mandible
Middle Aged
Molar, Third - surgery
Nerves
Patients
Prospective Studies
Regression analysis
Sex Factors
Smoking
Statistical analysis
Statistical significance
Surgery
Time Factors
wisdom teeth
Young Adult
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Summary:The aim of this study was to assess the influence of patients' and surgical variables on the onset and duration of action of local anesthesia (LA) in mandibular third‐molar (M3) surgery. Patients scheduled for mandibular M3 surgery were considered for inclusion in this prospective cohort study. Patients’ and surgical variables were recorded. Two per cent (2%) lidocaine with 1:100,000 epinephrine was used to block the nerves for extraction of mandibular M3. Then, the onset of action and duration of LA were monitored. Univariate analysis and multivariate regression analysis were used to analyze the data. The final cohort included 88 subjects (32 men and 56 women; mean age ± SD = 29.3 ± 12.3 yr). With univariate analysis, age, gender, body mass index (BMI), smoking quantity and duration, operation time, and ‘volume of local anesthetic needed’ significantly influenced the onset of action and duration of LA. Multivariate regression revealed that age and smoking quantity were the only statistically significant predictors of the onset of action of LA, whereas age, smoking quantity, and ‘volume of local anesthetic needed’ were the only statistically significant predictors of duration of LA. Further studies are recommended to uncover other predictors of the onset of action and duration of LA.
ISSN:0909-8836
1600-0722
DOI:10.1111/eos.12406