T1ρ mapping of articular cartilage grafts after autologous osteochondral transplantation for osteochondral lesions of the talus: A longitudinal evaluation

Background Clinical results of autologous osteochondral transplantation (AOT) for treatment of osteochondral lesions of the talus have been mixed. T1ρ imaging can be used to noninvasively detect early cartilage degeneration. Purpose or Hypothesis To quantitatively assess, by means of T1ρ imaging, ch...

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Bibliographic Details
Published in:Journal of magnetic resonance imaging 2018-08, Vol.48 (2), p.398-403
Main Authors: Haraguchi, Naoki, Ota, Koki, Nishida, Naoki, Ozeki, Takuma, Yoshida, Takashige, Tsutaya, Atsushi
Format: Article
Language:English
Subjects:
Ankle
Autografts
autologous osteochondral transplantation
Biocompatibility
Cartilage
Cartilage (articular)
Correlation analysis
Degeneration
Field strength
Grafting
Grafts
Imaging
Knee
Lesions
Magnetic resonance imaging
Mapping
Mathematical models
Model testing
osteochondral lesion
Population (statistical)
Population studies
Restoration
Statistical analysis
Statistical tests
T1ρ mapping
Talus
Transplantation
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Summary:Background Clinical results of autologous osteochondral transplantation (AOT) for treatment of osteochondral lesions of the talus have been mixed. T1ρ imaging can be used to noninvasively detect early cartilage degeneration. Purpose or Hypothesis To quantitatively assess, by means of T1ρ imaging, changes over time in the biochemical health of grafted cartilage after AOT for osteochondral lesions of the talus. Study Type Retrosepctive case series. Population The study group comprised nine patients who underwent AOT for an osteochondral lesion of the talus and in whom T1ρ mapping was performed 1 and 2 years postoperatively. Field Strength/Sequence 3 Tesla. T1ρ‐weighted turbo field echo. Assessment The mean T1ρ value of full‐thickness cartilage at the repair site and that of full‐thickness cartilage elsewhere in the same image (far‐field cartilage) were determined. Clinical assessment was based on the American Orthopaedic Foot & Ankle Society (AOFAS) scale. Correlation between the T1ρ ratios (grafted‐to‐far‐field cartilage T1ρ values) and clinical outcomes was examined. Statistical Tests Mixed effects model. Pearson correlation analysis. Results At 1 year, a significant difference existed between the mean T1ρ value of the grafted cartilage (57.0 ± 7.7 ms) and that of the far‐field cartilage (41.8 ± 4.6 ms) (P 
ISSN:1053-1807
1522-2586
DOI:10.1002/jmri.25962