A Cautionary Tale : Anaphylaxis to Isosulfan Blue Dye after 12 Years and 3339 Cases of Lymphatic Mapping

Sentinel node biopsy has become the standard method for lymphatic staging in early-stage breast cancer and melanomas. The most commonly used technique uses both a radioactive tracer as well as blue dye, usually isosulfan blue. In this report, we discuss two episodes of anaphylaxis to isosulfan blue...

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Bibliographic Details
Published in:The American surgeon 2008-02, Vol.74 (2), p.152-155
Main Authors: KAUFMAN, Gabriel, GUTH, Amber A, PACHTER, H. Leon, ROSES, Daniel F
Format: Article
Language:English
Subjects:
Aged
Airway management
Anaphylaxis - chemically induced
Biological and medical sciences
Biopsy
Blood pressure
Breast cancer
Clinical medicine
Coloring Agents - adverse effects
Female
General aspects
Humans
Lymphatic system
Male
Mammography
Medical sciences
Middle Aged
Nuclear medicine
Rosaniline Dyes - adverse effects
Sentinel Lymph Node Biopsy - methods
Sentinel Lymph Node Biopsy - statistics & numerical data
Time Factors
Vitamin A
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Summary:Sentinel node biopsy has become the standard method for lymphatic staging in early-stage breast cancer and melanomas. The most commonly used technique uses both a radioactive tracer as well as blue dye, usually isosulfan blue. In this report, we discuss two episodes of anaphylaxis to isosulfan blue during lymphatic mapping, occurring 12 years and 3339 lymphatic mapping cases after adoption of the technique, and discuss management issues raised by these events.
ISSN:0003-1348
1555-9823
DOI:10.1177/000313480807400214