Prognostic Value of The Lactate/Albumin Ratio for Predicting 28-Day Mortality in Critically ILL Sepsis Patients

AIM:The aim of this study was to evaluate the clinical utility of the lactate/albumin (L/A) ratio as a predictive factor of 28-day mortality in critically ill sepsis patients. METHODS:This is a retrospective observational study from a prospectively collected multicenter registry of 10 emergency depa...

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Published in:Shock (Augusta, Ga.) Ga.), 2018-11, Vol.50 (5), p.545-550
Main Authors: Shin, Jikyoung, Hwang, Sung Yeon, Jo, Ik Joon, Kim, Won Young, Ryoo, Seung Mok, Kang, Gu Hyun, Kim, Kyuseok, Jo, You Hwan, Chung, Sung Phil, Joo, Young Seon, Beom, Jin Ho, Yoon, Young Hoon, Han, Kap Su, Lim, Tae Ho, Choi, Han Sung, Kwon, Woon Yong, Suh, Gil Joon, Choi, Sung-Hyuk, Shin, Tae Gun
Format: Article
Language:English
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Summary:AIM:The aim of this study was to evaluate the clinical utility of the lactate/albumin (L/A) ratio as a predictive factor of 28-day mortality in critically ill sepsis patients. METHODS:This is a retrospective observational study from a prospectively collected multicenter registry of 10 emergency departments (EDs) in teaching hospitals that participated in the Korean Shock Society. It enrolled patients who were 19 years of age or older who had a suspected or confirmed infection and evidence of refractory hypotension or hypoperfusion. The prognostic performance of the L/A ratio and lactate level for predicting 28-day mortality was assessed. Lactate and albumin levels were measured immediately after ED arrival. RESULTS:A total of 946 patients were included, with 22.5% overall 28-day mortality. The area under the receiver operating characteristic curve (AUROC) value of the L/A ratio (0.69, 95% confidence interval [CI] 0.64–0.73, P 
ISSN:1073-2322
1540-0514
DOI:10.1097/SHK.0000000000001128