Health Utility of Pregnant Women Living with HIV/AIDS: Prevention of Mother-to-Child Transmission of HIV (PMTCT) Programs in Yunnan Province: A Cross-Sectional Study

• Published in: Value in health regional issues 2018-05, Vol.15, p.27-33
• Main Authors: Wang, Xiaowen, Guo, Guangping, Liang, Xiumin, Zhou, Ling, Zheng, Jiarui, Li, Shaoqin, Luo, Hongzhuan, Yang, Yuyan, Yang, Liyuan, Tan, Ting, Yu, Jun, Lu, Lin
• Format: Article
• Language: English
• Subjects: health utility; pregnant women living with HIV/AIDS; prevention mother-to-child transmission of HIV (PMTCT) programs; social support
• ISSN: 2212-1099; 2212-1102
• DOI: 10.1016/j.vhri.2017.05.004

Health utility (HU) is essential to understanding the effects of HIV infection as a chronic disease. No HU data on pregnant women living with human immunodeficiency virus (HIV) in Yunnan Province are available. This study aims to construct a database on HU and explore factors associated with HU by pregnant women living with HIV/acquired immunodeficiency syndrome (AIDS) who were enrolled in the Prevention of mother-to-child transmission of HIV (PMTCT) programs in Yunnan Province. A cross-sectional study was conducted in Yunnan Province on pregnant women living with HIV who were selected by convenience sampling. Sociodemographic, HIV-related, social support, and HU data were collected through face-to-face interviews. The European quality of life five-dimensional three-level (EQ-5D-3L) questionnaire and the social support rate scale (SSRS) were applied. One hundred and one pregnant women (mean age of 30.4 ± 5.1 years) participated in the survey. The mean EQ-5D index score and the EQ visual analogue scale (EQ-VAS) score of participants were 0.77 (95% confidence interval [CI] 0.74–0.79) and 75.77 (95% CI 75.00–80.00), respectively. The effect of social support on HU was maintained significant difference even after adjusting for such factors as education level, household income per year, and HIV disclosure, demonstrating a significant difference within EQ-5D index scores and EQ-VAS scores. Pregnant women living with HIV/AIDS who were enrolled in PMTCT programs reported the same level of HU as other patients living with HIV/AIDS. Integrating measurements of HU by using the EQ-5D-3L questionnaire could be helpful for economic evaluation of the PMTCT program. This study also suggests a potential benefit of appropriate social support.