Short-Term Outcome After Left Main Interventions in Patients Presenting With Acute Coronary Syndrome

• Published in: The Journal of invasive cardiology 2018-03, Vol.30 (3), p.98-104
• Main Authors: Obeid, Slayman, Yousif, Nooraldaem, Schelldorfer, Andreas, Shahin, Mohammady, Räber, Lorenz, Gencer, Baris, Mach, François, Roffi, Marco, Matter, Christian M, Windecker, Stephan, Lüscher, Thomas F
• Format: Article
• Language: English
• Subjects: Acute Coronary Syndrome - diagnosis; Acute Coronary Syndrome - epidemiology; Acute Coronary Syndrome - surgery; Aged; Aged, 80 and over; Coronary Angiography - methods; Coronary Vessels - diagnostic imaging; Coronary Vessels - surgery; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Outcome Assessment (Health Care); Percutaneous Coronary Intervention - adverse effects; Percutaneous Coronary Intervention - instrumentation; Percutaneous Coronary Intervention - methods; Percutaneous Coronary Intervention - statistics & numerical data; Postoperative Complications - diagnosis; Postoperative Complications - epidemiology; Risk Factors; Switzerland - epidemiology
• ISSN: 1557-2501

To assess the efficacy and safety of coronary left main (LM) disease interventions in patients with acute coronary syndromes (ACS) as compared to those without LM coronary artery disease. A total of 2899 patients with ACS, enrolled in the prospective Swiss Program University Medicine ACS (SPUM-ACS) cohort, were included. The primary endpoints of independently adjudicated major adverse cardiovascular and cerebrovascular event (MACCE) and net adverse clinical event (NACE) were determined at 30-day follow-up. Seventy-one (2.0%) of the 2899 ACS patients had significant LM disease. At 30-day follow-up, the primary outcomes of MACCE and NACE occurred in 140 patients (4.8%) and 272 patients (9.4%), respectively. Compared to those without LM disease, patients in the LM group were significantly older (P