Reversing Time: Ezh1 Deficiency Hastens Definitive Hematopoiesis

The inability to derive multipotent hematopoietic stem cells in vitro stems in part from a limited understanding of how multipotency is acquired during development. Recently in Nature,Vo et al. (2018) reveal the epigenetic enzyme Ezh1 as a master regulator of multipotency during hematopoietic stem c...

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Bibliographic Details
Published in:Cell stem cell 2018-03, Vol.22 (3), p.285-287
Main Authors: Apostol, April C., Beaudin, Anna E.
Format: Article
Language:English
Subjects:
Embryonic Development
Hematopoiesis
Hematopoietic Stem Cell Transplantation
Hematopoietic Stem Cells
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Summary:The inability to derive multipotent hematopoietic stem cells in vitro stems in part from a limited understanding of how multipotency is acquired during development. Recently in Nature,Vo et al. (2018) reveal the epigenetic enzyme Ezh1 as a master regulator of multipotency during hematopoietic stem cell development. The inability to derive multipotent hematopoietic stem cells in vitro stems in part from a limited understanding of how multipotency is acquired during development. Recently in Nature, Vo et al. (2018) reveal the epigenetic enzyme Ezh1 as a master regulator of multipotency during hematopoietic stem cell development.
ISSN:1934-5909
1875-9777
DOI:10.1016/j.stem.2018.02.006