Clinical and therapeutic aspects of prolactinoma in men

Macroprolactinomas predominate in males in comparison to microprolactinomas, with greater trend to invasiveness than in females. The clinical treatment has been the first option to prolactinomas, in both macro and microadenomas, irrespective the sex. We compared clinical presentation, prolactin leve...

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Bibliographic Details
Published in:Arquivos de neuro-psiquiatria 2003-12, Vol.61 (4), p.1004-1010
Main Authors: Braucks, Gisele Rieffel, Naliato, Erika Cesar de Oliveira, Tabet, Ana Lúcia Osorio, Gadelha, Monica Roberto, Violante, Alice Helena Dutra
Format: Article
Language:eng ; por ; spa
Subjects:
Adolescent
Adult
Age of Onset
Biomarkers
Bromocriptine - therapeutic use
Cabergoline
Chi-Square Distribution
Dopamine Agonists - therapeutic use
Ergolines - therapeutic use
Follow-Up Studies
Humans
Male
Middle Aged
Neoplasm Staging
Pituitary Neoplasms - blood
Pituitary Neoplasms - pathology
Pituitary Neoplasms - therapy
Prolactin - blood
Prolactinoma - blood
Prolactinoma - pathology
Prolactinoma - therapy
Statistics, Nonparametric
Treatment Outcome
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Summary:Macroprolactinomas predominate in males in comparison to microprolactinomas, with greater trend to invasiveness than in females. The clinical treatment has been the first option to prolactinomas, in both macro and microadenomas, irrespective the sex. We compared clinical presentation, prolactin levels, neuroradiologic invasiveness and prolactinemia response of 23 men with prolactinomas subjected to clinical therapy (group 1) with 19 who went also through surgical and/or radiotherapeutic treatment (group 2). The statistical analysis was done by the tests of chi-square or exact of Fisher, in order to compare proportions, and by t of Student or Mann-Whitney, in order to compare means. The level of significance adopted was 5% (p
ISSN:0004-282X
DOI:10.1590/S0004-282X2003000600022