Intravenous immunoglobulin in children with Guillain-Barré syndrome

We report our experience with intravenous immunoglobulin (IVIG), plasmapheresis and supportive care in 13 patients with the Guillain-Barré syndrome. Seven of 13 patients received IVIG, 2 plasmapheresis and 4 supportive care. At 15th day after IVIG administration, all patients in this group had impro...

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Bibliographic Details
Published in:Arquivos de neuro-psiquiatria 2000-12, Vol.58 (4), p.1081-1091
Main Authors: Bruck, I, Antoniuk, S A, Cat, R, Spessatto, A, Halick, S M, Bruyn, L R, Rodrigues, M, Scola, R H, Werneck, L C
Format: Article
Language:eng ; por
Subjects:
Child
Child, Preschool
Electromyography
Evoked Potentials, Motor
Female
Follow-Up Studies
Guillain-Barre Syndrome - therapy
Humans
Immunoglobulins, Intravenous - therapeutic use
Length of Stay
Male
Neural Conduction
Plasmapheresis
Severity of Illness Index
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Summary:We report our experience with intravenous immunoglobulin (IVIG), plasmapheresis and supportive care in 13 patients with the Guillain-Barré syndrome. Seven of 13 patients received IVIG, 2 plasmapheresis and 4 supportive care. At 15th day after IVIG administration, all patients in this group had improved at least one disability grade. In the plasmapheresis group, 1 improved at 5th day after the procedure. Two of the 4 patients that received supportive care improved at 20th day of evaluation. In the IVIG group, the final scores were lower and had no relapses. These results suggest faster clinical improvement with IVIG when compared with supportive measures.
ISSN:0004-282X
DOI:10.1590/S0004-282X2000000600016