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Nonreactive Human Immunodeficiency Virus Type 1 Rapid Tests After Sustained Viral Suppression Following Antiretroviral Therapy Initiation During Primary Infection
Early initiation of antiretroviral treatment during primary HIV infection led to negative HIV self-tests and point-of-care tests in 30% and 7%–9% of cases, respectively. These data reinforce the message that patients should never be retested after entering HIV care. Abstract We assessed the impact o...
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Published in: | The Journal of infectious diseases 2018-05, Vol.217 (11), p.1793-1797 |
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Main Authors: | , , , , , , , , , |
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container_end_page | 1797 |
container_issue | 11 |
container_start_page | 1793 |
container_title | The Journal of infectious diseases |
container_volume | 217 |
creator | Stefic, Karl Novelli, Sophie Mahjoub, Nadia Seng, Remonie Molina, Jean-Michel Cheneau, Christine Barin, Francis Chaix, Marie-Laure Meyer, Laurence Delaugerre, Constance |
description | Early initiation of antiretroviral treatment during primary HIV infection led to negative HIV self-tests and point-of-care tests in 30% and 7%–9% of cases, respectively. These data reinforce the message that patients should never be retested after entering HIV care.
Abstract
We assessed the impact of early antiretroviral treatment (ART) on human immunodeficiency virus (HIV) antibody detection by rapid tests in 44 individuals after several years of successful ART. HIV self-tests and point-of-care tests were negative in 30% and 7%–9% of cases, respectively. These data reinforce the message that patients should never be retested after entering HIV care. |
doi_str_mv | 10.1093/infdis/jiy120 |
format | article |
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Abstract
We assessed the impact of early antiretroviral treatment (ART) on human immunodeficiency virus (HIV) antibody detection by rapid tests in 44 individuals after several years of successful ART. HIV self-tests and point-of-care tests were negative in 30% and 7%–9% of cases, respectively. These data reinforce the message that patients should never be retested after entering HIV care.</description><identifier>ISSN: 0022-1899</identifier><identifier>EISSN: 1537-6613</identifier><identifier>DOI: 10.1093/infdis/jiy120</identifier><identifier>PMID: 29509924</identifier><language>eng</language><publisher>US: Oxford University Press</publisher><subject>Adult ; Anti-HIV Agents - therapeutic use ; Antiretroviral Therapy, Highly Active - methods ; Female ; HIV Antibodies - immunology ; HIV Infections - drug therapy ; HIV Infections - immunology ; HIV-1 - drug effects ; HIV-1 - immunology ; Humans ; Male ; Point-of-Care Testing ; Sustained Virologic Response ; Viral Load - methods</subject><ispartof>The Journal of infectious diseases, 2018-05, Vol.217 (11), p.1793-1797</ispartof><rights>The Author(s) 2018. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com. 2018</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c431t-9f374e8babc7156575d1e4b15110acc32a99029b280434285650367b319f2e443</citedby><cites>FETCH-LOGICAL-c431t-9f374e8babc7156575d1e4b15110acc32a99029b280434285650367b319f2e443</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29509924$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Stefic, Karl</creatorcontrib><creatorcontrib>Novelli, Sophie</creatorcontrib><creatorcontrib>Mahjoub, Nadia</creatorcontrib><creatorcontrib>Seng, Remonie</creatorcontrib><creatorcontrib>Molina, Jean-Michel</creatorcontrib><creatorcontrib>Cheneau, Christine</creatorcontrib><creatorcontrib>Barin, Francis</creatorcontrib><creatorcontrib>Chaix, Marie-Laure</creatorcontrib><creatorcontrib>Meyer, Laurence</creatorcontrib><creatorcontrib>Delaugerre, Constance</creatorcontrib><creatorcontrib>French National Agency for Research on AIDS and Viral Hepatitis (ANRS) PRIMO Study Group</creatorcontrib><creatorcontrib>French National Agency for Research on AIDS and Viral Hepatitis (ANRS) PRIMO Study Group</creatorcontrib><title>Nonreactive Human Immunodeficiency Virus Type 1 Rapid Tests After Sustained Viral Suppression Following Antiretroviral Therapy Initiation During Primary Infection</title><title>The Journal of infectious diseases</title><addtitle>J Infect Dis</addtitle><description>Early initiation of antiretroviral treatment during primary HIV infection led to negative HIV self-tests and point-of-care tests in 30% and 7%–9% of cases, respectively. These data reinforce the message that patients should never be retested after entering HIV care.
Abstract
We assessed the impact of early antiretroviral treatment (ART) on human immunodeficiency virus (HIV) antibody detection by rapid tests in 44 individuals after several years of successful ART. HIV self-tests and point-of-care tests were negative in 30% and 7%–9% of cases, respectively. These data reinforce the message that patients should never be retested after entering HIV care.</description><subject>Adult</subject><subject>Anti-HIV Agents - therapeutic use</subject><subject>Antiretroviral Therapy, Highly Active - methods</subject><subject>Female</subject><subject>HIV Antibodies - immunology</subject><subject>HIV Infections - drug therapy</subject><subject>HIV Infections - immunology</subject><subject>HIV-1 - drug effects</subject><subject>HIV-1 - immunology</subject><subject>Humans</subject><subject>Male</subject><subject>Point-of-Care Testing</subject><subject>Sustained Virologic Response</subject><subject>Viral Load - methods</subject><issn>0022-1899</issn><issn>1537-6613</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNqFkc1u1DAUhS1URKfTLtkiL9mE-trJZLwcFYaOVBUE024jx7kBV4kd_NNqXocnJWlKu6zuwro6n47tcwh5D-wTMCnOjW0bE87vzAE4e0MWUIgyW61AHJEFY5xnsJbymJyEcMcYy8WqfEeOuSyYlDxfkL_XznpUOpp7pJepV5bu-j5Z12BrtEGrD_TW-BTo_jAgBfpDDaahewwx0E0b0dOfKURlLDYTqLpxHwaPIRhn6dZ1nXsw9hfd2Gg8Ru_uH6H9b_RqONCdNdGoOLGfk5_A7970yk9Ki3oSTsnbVnUBz57OJbnZftlfXGZX377uLjZXmc4FxEy2osxxXatal1CsirJoAPMaCgCmtBZcScm4rPl6TCHn6xFhYxq1ANlyzHOxJB9n38G7P2n8YNWboLHrlEWXQsUZwJjrNEuSzaj2LgSPbTXMr66AVVMt1VxLNdcy8h-erFPdY_NM_-_h5W6Xhle8_gF5GZtF</recordid><startdate>20180505</startdate><enddate>20180505</enddate><creator>Stefic, Karl</creator><creator>Novelli, Sophie</creator><creator>Mahjoub, Nadia</creator><creator>Seng, Remonie</creator><creator>Molina, Jean-Michel</creator><creator>Cheneau, Christine</creator><creator>Barin, Francis</creator><creator>Chaix, Marie-Laure</creator><creator>Meyer, Laurence</creator><creator>Delaugerre, Constance</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20180505</creationdate><title>Nonreactive Human Immunodeficiency Virus Type 1 Rapid Tests After Sustained Viral Suppression Following Antiretroviral Therapy Initiation During Primary Infection</title><author>Stefic, Karl ; Novelli, Sophie ; Mahjoub, Nadia ; Seng, Remonie ; Molina, Jean-Michel ; Cheneau, Christine ; Barin, Francis ; Chaix, Marie-Laure ; Meyer, Laurence ; Delaugerre, Constance</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c431t-9f374e8babc7156575d1e4b15110acc32a99029b280434285650367b319f2e443</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adult</topic><topic>Anti-HIV Agents - therapeutic use</topic><topic>Antiretroviral Therapy, Highly Active - methods</topic><topic>Female</topic><topic>HIV Antibodies - immunology</topic><topic>HIV Infections - drug therapy</topic><topic>HIV Infections - immunology</topic><topic>HIV-1 - drug effects</topic><topic>HIV-1 - immunology</topic><topic>Humans</topic><topic>Male</topic><topic>Point-of-Care Testing</topic><topic>Sustained Virologic Response</topic><topic>Viral Load - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Stefic, Karl</creatorcontrib><creatorcontrib>Novelli, Sophie</creatorcontrib><creatorcontrib>Mahjoub, Nadia</creatorcontrib><creatorcontrib>Seng, Remonie</creatorcontrib><creatorcontrib>Molina, Jean-Michel</creatorcontrib><creatorcontrib>Cheneau, Christine</creatorcontrib><creatorcontrib>Barin, Francis</creatorcontrib><creatorcontrib>Chaix, Marie-Laure</creatorcontrib><creatorcontrib>Meyer, Laurence</creatorcontrib><creatorcontrib>Delaugerre, Constance</creatorcontrib><creatorcontrib>French National Agency for Research on AIDS and Viral Hepatitis (ANRS) PRIMO Study Group</creatorcontrib><creatorcontrib>French National Agency for Research on AIDS and Viral Hepatitis (ANRS) PRIMO Study Group</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Stefic, Karl</au><au>Novelli, Sophie</au><au>Mahjoub, Nadia</au><au>Seng, Remonie</au><au>Molina, Jean-Michel</au><au>Cheneau, Christine</au><au>Barin, Francis</au><au>Chaix, Marie-Laure</au><au>Meyer, Laurence</au><au>Delaugerre, Constance</au><aucorp>French National Agency for Research on AIDS and Viral Hepatitis (ANRS) PRIMO Study Group</aucorp><aucorp>French National Agency for Research on AIDS and Viral Hepatitis (ANRS) PRIMO Study Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Nonreactive Human Immunodeficiency Virus Type 1 Rapid Tests After Sustained Viral Suppression Following Antiretroviral Therapy Initiation During Primary Infection</atitle><jtitle>The Journal of infectious diseases</jtitle><addtitle>J Infect Dis</addtitle><date>2018-05-05</date><risdate>2018</risdate><volume>217</volume><issue>11</issue><spage>1793</spage><epage>1797</epage><pages>1793-1797</pages><issn>0022-1899</issn><eissn>1537-6613</eissn><abstract>Early initiation of antiretroviral treatment during primary HIV infection led to negative HIV self-tests and point-of-care tests in 30% and 7%–9% of cases, respectively. These data reinforce the message that patients should never be retested after entering HIV care.
Abstract
We assessed the impact of early antiretroviral treatment (ART) on human immunodeficiency virus (HIV) antibody detection by rapid tests in 44 individuals after several years of successful ART. HIV self-tests and point-of-care tests were negative in 30% and 7%–9% of cases, respectively. These data reinforce the message that patients should never be retested after entering HIV care.</abstract><cop>US</cop><pub>Oxford University Press</pub><pmid>29509924</pmid><doi>10.1093/infdis/jiy120</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Anti-HIV Agents - therapeutic use Antiretroviral Therapy, Highly Active - methods Female HIV Antibodies - immunology HIV Infections - drug therapy HIV Infections - immunology HIV-1 - drug effects HIV-1 - immunology Humans Male Point-of-Care Testing Sustained Virologic Response Viral Load - methods |
title | Nonreactive Human Immunodeficiency Virus Type 1 Rapid Tests After Sustained Viral Suppression Following Antiretroviral Therapy Initiation During Primary Infection |
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