Albumin–Bilirubin and Platelet–Albumin–Bilirubin Grades Do Not Predict Survival After Transjugular Intrahepatic Portosystemic Shunt Creation

Purpose To evaluate the capability of albumin–bilirubin (ALBI) and platelet–albumin–bilirubin (PALBI) grades in predicting transplant-free survival (TFS) in patients undergoing transjugular intrahepatic portosystemic shunt (TIPS) creation. Materials and Methods This single-center retrospective study...

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Bibliographic Details
Published in:Cardiovascular and interventional radiology 2018-07, Vol.41 (7), p.1029-1034
Main Authors: Khabbaz, Ramzy C., Lokken, R. Peter, Chen, Yi-Fan, Lipnik, Andrew J., Bui, James T., Ray, Charles E., Gaba, Ron C.
Format: Article
Language:English
Subjects:
Aged
Albumin
Ascites
Bilirubin
Bilirubin - blood
Bleeding
Blood Platelets
Cardiology
Cirrhosis
Clinical Investigation
Complications
Female
Follow-Up Studies
Humans
Hypertension
Imaging
Liver cirrhosis
Male
Medicine
Medicine & Public Health
Middle Aged
Nuclear Medicine
Patients
Platelets
Portasystemic Shunt, Transjugular Intrahepatic
Postoperative Complications - blood
Postoperative Complications - mortality
Prognosis
Radiology
Reproducibility of Results
Retrospective Studies
Serum albumin
Serum Albumin - analysis
Severity of Illness Index
Statistical analysis
Survival
Survival Analysis
Tips
Ultrasound
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Summary:Purpose To evaluate the capability of albumin–bilirubin (ALBI) and platelet–albumin–bilirubin (PALBI) grades in predicting transplant-free survival (TFS) in patients undergoing transjugular intrahepatic portosystemic shunt (TIPS) creation. Materials and Methods This single-center retrospective study included 342 ALBI and 337 PALBI patients (62% men; age 53–54 years) with cirrhosis (median MELD 15) and portal hypertension complications (variceal bleeding, 55%; ascites, 35%; other, 10%) who underwent TIPS between 1998 and 2017. Serum albumin, bilirubin, and platelet levels within 24 h prior to TIPS were used to calculate ALBI and PALBI grades. The influence of ALBI and PALBI grade on 30-day, 90-day, and overall post-TIPS TFS was assessed using C-indices, binary logistic regression, and the Cox proportional model, adjusting for Child–Pugh (CP) and MELD scores. Results The cohort spanned 110 (32%) and 232 (68%) ALBI grades 2 and 3 patients, and 40 (12%) and 297 (88%) PALBI grades 2 and 3 patients. While there were no differences in 30-day survival between ALBI and PALBI grades 2/3 ( P  > 0.05), 90-day and overall TFS showed statistically significant differences in survival between ALBI and PALBI grades 2/3 ( P  
ISSN:0174-1551
1432-086X
DOI:10.1007/s00270-018-1923-2