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Direct Dehydrogenative Arylation of Benzaldehydes with Arenes Using Transient Directing Groups

The utilization of the transient directing strategy into the direct oxidative dehydrogenative arylation of aldehydes with arenes was reported for the first time. Featured by mild reaction conditions, good functional group compatibility, and great regioselectivity, the method should find broad applic...

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Bibliographic Details
Published in:Organic letters 2018-04, Vol.20 (7), p.1794-1797
Main Authors: Wang, Da-Yu, Guo, Shi-Huan, Pan, Gao-Fei, Zhu, Xue-Qing, Gao, Ya-Ru, Wang, Yong-Qiang
Format: Article
Language:English
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Summary:The utilization of the transient directing strategy into the direct oxidative dehydrogenative arylation of aldehydes with arenes was reported for the first time. Featured by mild reaction conditions, good functional group compatibility, and great regioselectivity, the method should find broad applications in new medicine and material development and discovery processes.
ISSN:1523-7060
1523-7052
DOI:10.1021/acs.orglett.8b00292